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What has changed in the prevalence of hypertension in dialyzed children during the last decade?

Background: Hypertension very often accompanies progression of chronic kidney disease (CKD) in children. A cross-sectional analysis of hypertension prevalence in dialyzed children in Poland was designed with a comparison with the data previously recorded 10 years earlier. Methods: Two cohorts of chi...

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Autores principales: Tkaczyk, Marcin, Stańczyk, Małgorzata, Miklaszewska, Monika, Zachwieja, Katarzyna, Wierciński, Ryszard, Stankiewicz, Roman, Firszt-Adamczyk, Agnieszka, Zachwieja, Jacek, Borzęcka, Halina, Zagożdżon, Ilona, Leszczyńska, Beata, Medyńska, Anna, Adamczyk, Piotr, Szczepańska, Maria, Fendler, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014511/
https://www.ncbi.nlm.nih.gov/pubmed/27882810
http://dx.doi.org/10.1080/0886022X.2016.1260033
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author Tkaczyk, Marcin
Stańczyk, Małgorzata
Miklaszewska, Monika
Zachwieja, Katarzyna
Wierciński, Ryszard
Stankiewicz, Roman
Firszt-Adamczyk, Agnieszka
Zachwieja, Jacek
Borzęcka, Halina
Zagożdżon, Ilona
Leszczyńska, Beata
Medyńska, Anna
Adamczyk, Piotr
Szczepańska, Maria
Fendler, Wojciech
author_facet Tkaczyk, Marcin
Stańczyk, Małgorzata
Miklaszewska, Monika
Zachwieja, Katarzyna
Wierciński, Ryszard
Stankiewicz, Roman
Firszt-Adamczyk, Agnieszka
Zachwieja, Jacek
Borzęcka, Halina
Zagożdżon, Ilona
Leszczyńska, Beata
Medyńska, Anna
Adamczyk, Piotr
Szczepańska, Maria
Fendler, Wojciech
author_sort Tkaczyk, Marcin
collection PubMed
description Background: Hypertension very often accompanies progression of chronic kidney disease (CKD) in children. A cross-sectional analysis of hypertension prevalence in dialyzed children in Poland was designed with a comparison with the data previously recorded 10 years earlier. Methods: Two cohorts of children were analyzed: 59 subjects dialyzed in 2013, and 134 children from the previous study performed in 2003 that were reevaluated according to the current methodology. The incidence of hypertension (defined by SDS of sBP or dBP >1.64), clinical data, medical history, dialysis modalities and selected biochemical parameters of dialysis adequacy were analyzed. Results: The prevalence of hypertension increased from 64% in 2003 to 78% in 2013. The efficacy of antihypertensive treatment remained unsatisfactory (61% proper BP control). Preservation of residual urine output and strict fluid balance may prevent development of hypertension in children on dialysis. Conclusions: Despite the higher awareness of hypertension and its complications in dialyzed children, the incidence of this entity has increased during the last decade, with the percentage of undertreated patients comparable to that observed 10 years ago. Thus, more attention should be paid to therapy efficacy in this population to prevent further damage to the cardiovascular system and to decrease morbidity.
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spelling pubmed-60145112018-06-28 What has changed in the prevalence of hypertension in dialyzed children during the last decade? Tkaczyk, Marcin Stańczyk, Małgorzata Miklaszewska, Monika Zachwieja, Katarzyna Wierciński, Ryszard Stankiewicz, Roman Firszt-Adamczyk, Agnieszka Zachwieja, Jacek Borzęcka, Halina Zagożdżon, Ilona Leszczyńska, Beata Medyńska, Anna Adamczyk, Piotr Szczepańska, Maria Fendler, Wojciech Ren Fail Clinical Study Background: Hypertension very often accompanies progression of chronic kidney disease (CKD) in children. A cross-sectional analysis of hypertension prevalence in dialyzed children in Poland was designed with a comparison with the data previously recorded 10 years earlier. Methods: Two cohorts of children were analyzed: 59 subjects dialyzed in 2013, and 134 children from the previous study performed in 2003 that were reevaluated according to the current methodology. The incidence of hypertension (defined by SDS of sBP or dBP >1.64), clinical data, medical history, dialysis modalities and selected biochemical parameters of dialysis adequacy were analyzed. Results: The prevalence of hypertension increased from 64% in 2003 to 78% in 2013. The efficacy of antihypertensive treatment remained unsatisfactory (61% proper BP control). Preservation of residual urine output and strict fluid balance may prevent development of hypertension in children on dialysis. Conclusions: Despite the higher awareness of hypertension and its complications in dialyzed children, the incidence of this entity has increased during the last decade, with the percentage of undertreated patients comparable to that observed 10 years ago. Thus, more attention should be paid to therapy efficacy in this population to prevent further damage to the cardiovascular system and to decrease morbidity. Taylor & Francis 2016-11-24 /pmc/articles/PMC6014511/ /pubmed/27882810 http://dx.doi.org/10.1080/0886022X.2016.1260033 Text en © 2016 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Tkaczyk, Marcin
Stańczyk, Małgorzata
Miklaszewska, Monika
Zachwieja, Katarzyna
Wierciński, Ryszard
Stankiewicz, Roman
Firszt-Adamczyk, Agnieszka
Zachwieja, Jacek
Borzęcka, Halina
Zagożdżon, Ilona
Leszczyńska, Beata
Medyńska, Anna
Adamczyk, Piotr
Szczepańska, Maria
Fendler, Wojciech
What has changed in the prevalence of hypertension in dialyzed children during the last decade?
title What has changed in the prevalence of hypertension in dialyzed children during the last decade?
title_full What has changed in the prevalence of hypertension in dialyzed children during the last decade?
title_fullStr What has changed in the prevalence of hypertension in dialyzed children during the last decade?
title_full_unstemmed What has changed in the prevalence of hypertension in dialyzed children during the last decade?
title_short What has changed in the prevalence of hypertension in dialyzed children during the last decade?
title_sort what has changed in the prevalence of hypertension in dialyzed children during the last decade?
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014511/
https://www.ncbi.nlm.nih.gov/pubmed/27882810
http://dx.doi.org/10.1080/0886022X.2016.1260033
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