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ATRA attenuate proteinuria via downregulation of TRPC6 in glomerulosclerosis rats induced by adriamycin

Objective: In this research, we explored the molecular mechanism of proteinuria in glomerulosclerosis rats and the protective effects of ATRA. Methods: This research set up three groups: SHO group, GS group, and ATRA group (15 mg/(kg d), Sigma, St. Louis, MO). The serum creatinine (Scr), urea nitrog...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Chen, Xiu-Ping, Qin, He, Jiang, Ling, Qin, Yuan-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014515/
https://www.ncbi.nlm.nih.gov/pubmed/29619864
http://dx.doi.org/10.1080/0886022X.2018.1456459