Binimetinib (MEK162) in recurrent low-grade serous ovarian cancer resistant to chemotherapy and hormonal treatment

BACKGROUND: Management of advanced/recurrent low-grade serous ovarian carcinoma (LGOSC) is often challenging. Effective treatment options remain limited for hormone and chemotherapy-resistant LGSOC. CASE: A 65-year-old woman with recurrent widespread LGSOC harboring the KRAS-G12 V hotspot mutation e...

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Detalles Bibliográficos
Autores principales: Han, Chanhee, Bellone, Stefania, Zammataro, Luca, Schwartz, Peter E., Santin, Alessandro D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014583/
https://www.ncbi.nlm.nih.gov/pubmed/29946554
http://dx.doi.org/10.1016/j.gore.2018.05.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014583/
https://www.ncbi.nlm.nih.gov/pubmed/29946554
http://dx.doi.org/10.1016/j.gore.2018.05.011

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