Transition Metal-Free 1,2-Carboboration of Unactivated Alkenes

[Image: see text] A method for transition metal-free 1,2-carboboration of unactivated alkenes with bis(catecholato)diboron as the boron source in combination with alkyl halides as the alkyl component is introduced. The three-component reaction proceeds via a radical pathway on a broad range of unact...

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Autores principales: Cheng, Ying, Mück-Lichtenfeld, Christian, Studer, Armido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014685/
https://www.ncbi.nlm.nih.gov/pubmed/29741375
http://dx.doi.org/10.1021/jacs.8b03333
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author Cheng, Ying
Mück-Lichtenfeld, Christian
Studer, Armido
author_facet Cheng, Ying
Mück-Lichtenfeld, Christian
Studer, Armido
author_sort Cheng, Ying
collection PubMed
description [Image: see text] A method for transition metal-free 1,2-carboboration of unactivated alkenes with bis(catecholato)diboron as the boron source in combination with alkyl halides as the alkyl component is introduced. The three-component reaction proceeds via a radical pathway on a broad range of unactivated alkenes, and the 1,2-carboboration products serve as valuable synthetic building blocks. Density functional theory calculations provide insights into the mechanism.
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spelling pubmed-60146852018-06-25 Transition Metal-Free 1,2-Carboboration of Unactivated Alkenes Cheng, Ying Mück-Lichtenfeld, Christian Studer, Armido J Am Chem Soc [Image: see text] A method for transition metal-free 1,2-carboboration of unactivated alkenes with bis(catecholato)diboron as the boron source in combination with alkyl halides as the alkyl component is introduced. The three-component reaction proceeds via a radical pathway on a broad range of unactivated alkenes, and the 1,2-carboboration products serve as valuable synthetic building blocks. Density functional theory calculations provide insights into the mechanism. American Chemical Society 2018-05-09 2018-05-23 /pmc/articles/PMC6014685/ /pubmed/29741375 http://dx.doi.org/10.1021/jacs.8b03333 Text en Copyright © 2018 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Cheng, Ying
Mück-Lichtenfeld, Christian
Studer, Armido
Transition Metal-Free 1,2-Carboboration of Unactivated Alkenes
title Transition Metal-Free 1,2-Carboboration of Unactivated Alkenes
title_full Transition Metal-Free 1,2-Carboboration of Unactivated Alkenes
title_fullStr Transition Metal-Free 1,2-Carboboration of Unactivated Alkenes
title_full_unstemmed Transition Metal-Free 1,2-Carboboration of Unactivated Alkenes
title_short Transition Metal-Free 1,2-Carboboration of Unactivated Alkenes
title_sort transition metal-free 1,2-carboboration of unactivated alkenes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014685/
https://www.ncbi.nlm.nih.gov/pubmed/29741375
http://dx.doi.org/10.1021/jacs.8b03333
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AT studerarmido transitionmetalfree12carboborationofunactivatedalkenes

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