Chalcomoracin is a potent anticancer agent acting through triggering Oxidative stress via a mitophagy- and paraptosis-dependent mechanism

Chalocomoracin (CMR), one of the major secondary metabolites found in fungus-infected mulberry leaves, is a potent anticancer agent. However, its anticancer mechanism remains elusive. Here, we demonstrated the potent anti-tumor activity and molecular mechanism of CMR both in vitro and in vivo. We sh...

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Detalles Bibliográficos
Autores principales: Han, Haote, Chou, Chih-Chien, Li, Ruyi, Liu, Jiangyun, Zhang, Lin, Zhu, Wei, Hu, Jin, Yang, Bingxian, Tian, Jingkui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014977/
https://www.ncbi.nlm.nih.gov/pubmed/29934599
http://dx.doi.org/10.1038/s41598-018-27724-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014977/
https://www.ncbi.nlm.nih.gov/pubmed/29934599
http://dx.doi.org/10.1038/s41598-018-27724-3

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