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GRAMD1B regulates cell migration in breast cancer cells through JAK/STAT and Akt signaling

Dysregulated JAK/STAT signaling has been implicated in breast cancer metastasis, which is associated with high relapse risks. However, mechanisms underlying JAK/STAT signaling-mediated breast tumorigenesis are poorly understood. Here, we showed that GRAMD1B expression is upregulated on IL-6 but down...

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Detalles Bibliográficos
Autores principales: Khanna, Puja, Lee, Joan Shuying, Sereemaspun, Amornpun, Lee, Haeryun, Baeg, Gyeong Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015000/
https://www.ncbi.nlm.nih.gov/pubmed/29934528
http://dx.doi.org/10.1038/s41598-018-27864-6