Expression ratio of the TGFβ-inducible gene MYO10 is prognostic for overall survival of squamous cell lung cancer patients and predicts chemotherapy response

In lung cancer a deregulation of Transforming Growth Factor-β (TGFβ) signaling has been observed. Yet, the impact of TGFβ in squamous cell carcinoma of the lung (LUSC) remained to be determined. We combined phenotypic and transcriptome-wide studies and showed that the stimulation of the LUSC cell li...

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Detalles Bibliográficos
Autores principales: Dvornikov, D., Schneider, M. A., Ohse, S., Szczygieł, M., Titkova, I., Rosenblatt, M., Muley, T., Warth, A., Herth, F. J., Dienemann, H., Thomas, M., Timmer, J., Schilling, M., Busch, H., Boerries, M., Meister, M., Klingmüller, U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015003/
https://www.ncbi.nlm.nih.gov/pubmed/29934580
http://dx.doi.org/10.1038/s41598-018-27912-1

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