Secondary lymphoid organ fibroblastic reticular cells mediate trans-infection of HIV-1 via CD44-hyaluronan interactions

Fibroblastic reticular cells (FRCs) are stromal cells in secondary lymphoid organs, the major sites for HIV-1 infection of CD4(+) T cells. Although FRCs regulate T cell survival, proliferation, and migration, whether they play any role in HIV-1 spread has not been studied. Here, we show that FRCs en...

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Detalles Bibliográficos
Autores principales: Murakami, Tomoyuki, Kim, Jiwon, Li, Yi, Green, Glenn Edward, Shikanov, Ariella, Ono, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015004/
https://www.ncbi.nlm.nih.gov/pubmed/29934525
http://dx.doi.org/10.1038/s41467-018-04846-w

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