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Pyruvate dehydrogenase complex plays a central role in brown adipocyte energy expenditure and fuel utilization during short-term beta-adrenergic activation
Activation of brown adipose tissue (BAT) contributes to total body energy expenditure through energy dissipation as heat. Activated BAT increases the clearance of lipids and glucose from the circulation, but how BAT accommodates large influx of multiple substrates is not well defined. The purpose of...
Autores principales: | Held, Ntsiki M., Kuipers, Eline N., van Weeghel, Michel, van Klinken, Jan Bert, Denis, Simone W., Lombès, Marc, Wanders, Ronald J., Vaz, Frédéric M., Rensen, Patrick C. N., Verhoeven, Arthur J., Boon, Mariëtte R., Houtkooper, Riekelt H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015083/ https://www.ncbi.nlm.nih.gov/pubmed/29934543 http://dx.doi.org/10.1038/s41598-018-27875-3 |
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