Xanthine Oxidase Inhibitor Allopurinol Prevents Oxidative Stress‐Mediated Atrial Remodeling in Alloxan‐Induced Diabetes Mellitus Rabbits

BACKGROUND: There are several mechanisms, including inflammation, oxidative stress and abnormal calcium homeostasis, involved in the pathogenesis of atrial fibrillation. In diabetes mellitus (DM), increased oxidative stress may be attributable to higher xanthine oxidase activity. In this study, we e...

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Detalles Bibliográficos
Autores principales: Yang, Yajuan, Zhao, Jianping, Qiu, Jiuchun, Li, Jian, Liang, Xue, Zhang, Zhiwei, Zhang, Xiaowei, Fu, Huaying, Korantzopoulos, Panagiotis, Letsas, Konstantinos P., Tse, Gary, Li, Guangping, Liu, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015332/
https://www.ncbi.nlm.nih.gov/pubmed/29720500
http://dx.doi.org/10.1161/JAHA.118.008807