Aryl Hydrocarbon Receptor Nuclear Translocator in Vascular Smooth Muscle Cells Is Required for Optimal Peripheral Perfusion Recovery

BACKGROUND: Limb ischemia resulting from peripheral vascular disease is a common cause of morbidity. Vessel occlusion limits blood flow, creating a hypoxic environment that damages distal tissue, requiring therapeutic revascularization. Hypoxia‐inducible factors (HIFs) are key transcriptional regula...

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Detalles Bibliográficos
Autores principales: Borton, Anna Henry, Benson, Bryan L., Neilson, Lee E., Saunders, Ashley, Alaiti, M. Amer, Huang, Alex Y., Jain, Mukesh K., Proweller, Aaron, Ramirez‐Bergeron, Diana L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015385/
https://www.ncbi.nlm.nih.gov/pubmed/29858371
http://dx.doi.org/10.1161/JAHA.118.009205

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