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Estrogen Deficiency Promotes Cerebral Aneurysm Rupture by Upregulation of Th17 Cells and Interleukin‐17A Which Downregulates E‐Cadherin

BACKGROUND: Estrogen deficiency is associated with the development of cerebral aneurysms; however, the mechanism remains unknown. We explored the pathway of cerebral aneurysm development by investigating the potential link between estrogen deficiency and inflammatory factors. METHODS AND RESULTS: Fi...

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Detalles Bibliográficos
Autores principales: Hoh, Brian L., Rojas, Kelley, Lin, Li, Fazal, Hanain Z., Hourani, Siham, Nowicki, Kamil W., Schneider, Matheus B., Hosaka, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015422/
https://www.ncbi.nlm.nih.gov/pubmed/29654199
http://dx.doi.org/10.1161/JAHA.118.008863