Closed Or Open after Source Control Laparotomy for Severe Complicated Intra-Abdominal Sepsis (the COOL trial): study protocol for a randomized controlled trial

BACKGROUND: Severe complicated intra-abdominal sepsis (SCIAS) has an increasing incidence with mortality rates over 80% in some settings. Mortality typically results from disruption of the gastrointestinal tract, progressive and self-perpetuating bio-mediator generation, systemic inflammation, and m...

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Detalles Bibliográficos
Autores principales: Kirkpatrick, Andrew W., Coccolini, Federico, Ansaloni, Luca, Roberts, Derek J., Tolonen, Matti, McKee, Jessica L., Leppaniemi, Ari, Faris, Peter, Doig, Christopher J., Catena, Fausto, Fabian, Timothy, Jenne, Craig N., Chiara, Osvaldo, Kubes, Paul, Manns, Braden, Kluger, Yoram, Fraga, Gustavo P., Pereira, Bruno M., Diaz, Jose J., Sugrue, Michael, Moore, Ernest E., Ren, Jianan, Ball, Chad G., Coimbra, Raul, Balogh, Zsolt J., Abu-Zidan, Fikri M., Dixon, Elijah, Biffl, Walter, MacLean, Anthony, Ball, Ian, Drover, John, McBeth, Paul B., Posadas-Calleja, Juan G., Parry, Neil G., Di Saverio, Salomone, Ordonez, Carlos A., Xiao, Jimmy, Sartelli, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015449/
https://www.ncbi.nlm.nih.gov/pubmed/29977328
http://dx.doi.org/10.1186/s13017-018-0183-4

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