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Alzheimer’s disease master regulators analysis: search for potential molecular targets and drug repositioning candidates

BACKGROUND: Alzheimer’s disease (AD) is a multifactorial and complex neuropathology that involves impairment of many intricate molecular mechanisms. Despite recent advances, AD pathophysiological characterization remains incomplete, which hampers the development of effective treatments. In fact, cur...

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Detalles Bibliográficos
Autores principales: Vargas, D. M., De Bastiani, M. A., Zimmer, E. R., Klamt, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015462/
https://www.ncbi.nlm.nih.gov/pubmed/29935546
http://dx.doi.org/10.1186/s13195-018-0394-7