Metastatic cancers promote cachexia through altered zinc homeostasis in skeletal muscle

Metastatic cancer patients experience a severe loss of skeletal muscle mass and function known as cachexia. Cachexia is associated with poor prognosis and accelerated death in cancer patients, yet its underlying mechanisms remain poorly understood. Here, we identify the metal transporter ZIP14 as a...

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Detalles Bibliográficos
Autores principales: Wang, Gang, Biswas, Anup K., Ma, Wanchao, Kandpal, Manoj, Coker, Courtney, Grandgenett, Paul M., Hollingsworth, Michael A., Jain, Rinku, Tanji, Kurenai, Lόpez-Pintado, Sara, Borczuk, Alain, Hebert, Doreen, Jenkitkasemwong, Supak, Hojyo, Shintaro, Davuluri, Ramana, Knutson, Mitchell D., Fukada, Toshiyuki, Acharyya, Swarnali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015555/
https://www.ncbi.nlm.nih.gov/pubmed/29875463
http://dx.doi.org/10.1038/s41591-018-0054-2

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