Cargando…
SHP2-Mediated Signal Networks in Stem Cell Homeostasis and Dysfunction
Stem cells, including embryonic stem cells (ESCs) and adult stem cells, play a central role in mammal organism development and homeostasis. They have two unique properties: the capacity for self-renewal and the ability to differentiate into many specialized cell types. Src homology region 2- (SH2-)...
Autores principales: | Kan, Chen, Yang, Fan, Wang, Siying |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015663/ https://www.ncbi.nlm.nih.gov/pubmed/29983715 http://dx.doi.org/10.1155/2018/8351374 |
Ejemplares similares
-
SHP2 inhibition enhances the anticancer effect of Osimertinib in EGFR T790M mutant lung adenocarcinoma by blocking CXCL8 loop mediated stemness
por: Xia, Leiming, et al.
Publicado: (2021) -
The Cell-Specific Role of SHP2 in Regulating Bone Homeostasis and Regeneration Niches
por: Zhang, Jie, et al.
Publicado: (2023) -
Shp1 regulates T cell homeostasis by limiting IL-4 signals
por: Johnson, Dylan J., et al.
Publicado: (2013) -
SHP-2 and PD-1-SHP-2 signaling regulate myeloid cell differentiation and antitumor responses
por: Christofides, Anthos, et al.
Publicado: (2022) -
Role of the Protein Tyrosine Phosphatase Shp2 in Homeostasis of the Intestinal Epithelium
por: Yamashita, Hironori, et al.
Publicado: (2014)