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Asymmetric Bilateral Lichen Striatus: A Rare Presentation following Multiple Blaschko's Lines

Lichen striatus (LS) is an uncommon, acquired, self-limited, and benign linear dermatosis of unknown etiology that most often occurs unilaterally and is confined to the lines of Blaschko. A healthy 7-year-old girl presented to our clinic with bilateral asymmetric LS occurring on the right arm and le...

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Autores principales: Dickman, Jeffrey S., Frandsen, McKay D., Racette, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015711/
https://www.ncbi.nlm.nih.gov/pubmed/29984008
http://dx.doi.org/10.1155/2018/6905175
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author Dickman, Jeffrey S.
Frandsen, McKay D.
Racette, Andrew J.
author_facet Dickman, Jeffrey S.
Frandsen, McKay D.
Racette, Andrew J.
author_sort Dickman, Jeffrey S.
collection PubMed
description Lichen striatus (LS) is an uncommon, acquired, self-limited, and benign linear dermatosis of unknown etiology that most often occurs unilaterally and is confined to the lines of Blaschko. A healthy 7-year-old girl presented to our clinic with bilateral asymmetric LS occurring on the right arm and left leg of 1-year duration. Very few cases of bilateral LS have been previously reported in the literature, with none from clinics within the United States. The etiology of LS is currently unknown; however its confinement to Blaschko's lines, which represent embryologic migration of skin cell clones, does provide insight into a possible pathogenesis. It seems most likely that an individual's development of LS is linked to their genetic predisposition and a subsequent triggering event. Our case serves as a strong example of a rare presentation of LS and facilitates discussion of the clinical diagnostic process and possible pathogenesis of this dermatosis.
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spelling pubmed-60157112018-07-08 Asymmetric Bilateral Lichen Striatus: A Rare Presentation following Multiple Blaschko's Lines Dickman, Jeffrey S. Frandsen, McKay D. Racette, Andrew J. Case Rep Dermatol Med Case Report Lichen striatus (LS) is an uncommon, acquired, self-limited, and benign linear dermatosis of unknown etiology that most often occurs unilaterally and is confined to the lines of Blaschko. A healthy 7-year-old girl presented to our clinic with bilateral asymmetric LS occurring on the right arm and left leg of 1-year duration. Very few cases of bilateral LS have been previously reported in the literature, with none from clinics within the United States. The etiology of LS is currently unknown; however its confinement to Blaschko's lines, which represent embryologic migration of skin cell clones, does provide insight into a possible pathogenesis. It seems most likely that an individual's development of LS is linked to their genetic predisposition and a subsequent triggering event. Our case serves as a strong example of a rare presentation of LS and facilitates discussion of the clinical diagnostic process and possible pathogenesis of this dermatosis. Hindawi 2018-06-10 /pmc/articles/PMC6015711/ /pubmed/29984008 http://dx.doi.org/10.1155/2018/6905175 Text en Copyright © 2018 Jeffrey S. Dickman et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Dickman, Jeffrey S.
Frandsen, McKay D.
Racette, Andrew J.
Asymmetric Bilateral Lichen Striatus: A Rare Presentation following Multiple Blaschko's Lines
title Asymmetric Bilateral Lichen Striatus: A Rare Presentation following Multiple Blaschko's Lines
title_full Asymmetric Bilateral Lichen Striatus: A Rare Presentation following Multiple Blaschko's Lines
title_fullStr Asymmetric Bilateral Lichen Striatus: A Rare Presentation following Multiple Blaschko's Lines
title_full_unstemmed Asymmetric Bilateral Lichen Striatus: A Rare Presentation following Multiple Blaschko's Lines
title_short Asymmetric Bilateral Lichen Striatus: A Rare Presentation following Multiple Blaschko's Lines
title_sort asymmetric bilateral lichen striatus: a rare presentation following multiple blaschko's lines
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015711/
https://www.ncbi.nlm.nih.gov/pubmed/29984008
http://dx.doi.org/10.1155/2018/6905175
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