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Diet-Induced Growth Is Regulated via Acquired Leptin Resistance and Engages a Pomc-Somatostatin-Growth Hormone Circuit
Anorexigenic pro-opiomelanocortin (Pomc)/alpha-melanocyte stimulating hormone (αMSH) neurons of the hypothalamic melanocortin system function as key regulators of energy homeostasis, also controlling somatic growth across different species. However, the mechanisms of melanocortin-dependent growth co...
Autores principales: | Löhr, Heiko, Hess, Simon, Pereira, Mafalda M.A., Reinoß, Philip, Leibold, Sandra, Schenkel, Christel, Wunderlich, Claudia M., Kloppenburg, Peter, Brüning, Jens C., Hammerschmidt, Matthias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015746/ https://www.ncbi.nlm.nih.gov/pubmed/29742429 http://dx.doi.org/10.1016/j.celrep.2018.04.018 |
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