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Conformational Flexibility in the CD81-Binding Site of the Hepatitis C Virus Glycoprotein E2

Numerous antibodies have been described that potently neutralize a broad range of hepatitis C virus (HCV) isolates and the majority of these antibodies target the binding site for the cellular receptor CD81 within the major HCV glycoprotein E2. A detailed understanding of the major antigenic determi...

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Detalles Bibliográficos
Autores principales: Ströh, Luisa J., Nagarathinam, Kumar, Krey, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015841/
https://www.ncbi.nlm.nih.gov/pubmed/29967619
http://dx.doi.org/10.3389/fimmu.2018.01396