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Conformational Flexibility in the CD81-Binding Site of the Hepatitis C Virus Glycoprotein E2
Numerous antibodies have been described that potently neutralize a broad range of hepatitis C virus (HCV) isolates and the majority of these antibodies target the binding site for the cellular receptor CD81 within the major HCV glycoprotein E2. A detailed understanding of the major antigenic determi...
Autores principales: | Ströh, Luisa J., Nagarathinam, Kumar, Krey, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015841/ https://www.ncbi.nlm.nih.gov/pubmed/29967619 http://dx.doi.org/10.3389/fimmu.2018.01396 |
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