Glioblastoma Stem-Like Cells Are More Susceptible Than Differentiated Cells to Natural Killer Cell Lysis Mediated Through Killer Immunoglobulin-Like Receptors–Human Leukocyte Antigen Ligand Mismatch and Activation Receptor–Ligand Interactions

Glioblastoma (GBM) is the most aggressive brain malignancy in adults, where survival is approximately 14.6 months. Novel therapies are urgently needed and immunotherapy has hailed a new dawn for treatment of solid tumors. Natural killer (NK) cells may be amenable therapeutic effectors against hetero...

Descripción completa

Detalles Bibliográficos
Autores principales: Haspels, Heleen Neeltje, Rahman, Mohummad Aminur, Joseph, Justin Vareecal, Gras Navarro, Andrea, Chekenya, Martha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015895/
https://www.ncbi.nlm.nih.gov/pubmed/29967607
http://dx.doi.org/10.3389/fimmu.2018.01345

Ejemplares similares

Ejemplares similares