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High-Throughput Screening of Type III Secretion Determinants Reveals a Major Chaperone-Independent Pathway

Numerous Gram-negative bacterial pathogens utilize type III secretion systems (T3SSs) to inject tens of effector proteins directly into the cytosol of host cells. Through interactions with cognate chaperones, type III effectors are defined and recruited to the sorting platform, a cytoplasmic compone...

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Detalles Bibliográficos
Autores principales:	Ernst, Nadja Heinz, Reeves, Analise Z., Ramseyer, Julia E., Lesser, Cammie F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016238/ https://www.ncbi.nlm.nih.gov/pubmed/29921672 http://dx.doi.org/10.1128/mBio.01050-18

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