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Activation of Sonic Hedgehog Signaling Is Associated with Human Osteosarcoma Cells Radioresistance Characterized by Increased Proliferation, Migration, and Invasion

BACKGROUND: Radioresistance restricts the application of radiotherapy in human osteosarcoma (OS). This study investigated the molecular mechanism of radioresistance in OS, which may provide clues to finding ideal targets for genetic therapy. MATERILA/METHODS: The human OS cell line MG63 was employed...

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Detalles Bibliográficos
Autores principales: Qu, Wei, Li, Dichen, Wang, Yufei, Wu, Qining, Hao, Dingjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016436/
https://www.ncbi.nlm.nih.gov/pubmed/29864766
http://dx.doi.org/10.12659/MSM.908278