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Implementing pharmacogenomics decision support across seven European countries: The Ubiquitous Pharmacogenomics (U-PGx) project

Clinical pharmacogenomics (PGx) has the potential to make pharmacotherapy safer and more effective by utilizing genetic patient data for drug dosing and selection. However, widespread adoption of PGx depends on its successful integration into routine clinical care through clinical decision support t...

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Detalles Bibliográficos
Autores principales: Blagec, Kathrin, Koopmann, Rudolf, Crommentuijn – van Rhenen, Mandy, Holsappel, Inge, van der Wouden, Cathelijne H, Konta, Lidija, Xu, Hong, Steinberger, Daniela, Just, Enrico, Swen, Jesse J, Guchelaar, Henk-Jan, Samwald, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016647/
https://www.ncbi.nlm.nih.gov/pubmed/29444243
http://dx.doi.org/10.1093/jamia/ocy005
Descripción
Sumario:Clinical pharmacogenomics (PGx) has the potential to make pharmacotherapy safer and more effective by utilizing genetic patient data for drug dosing and selection. However, widespread adoption of PGx depends on its successful integration into routine clinical care through clinical decision support tools, which is often hampered by insufficient or fragmented infrastructures. This paper describes the setup and implementation of a unique multimodal, multilingual clinical decision support intervention consisting of digital, paper-, and mobile-based tools that are deployed across implementation sites in seven European countries participating in the Ubiquitous PGx (U-PGx) project.