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Implementing pharmacogenomics decision support across seven European countries: The Ubiquitous Pharmacogenomics (U-PGx) project

Clinical pharmacogenomics (PGx) has the potential to make pharmacotherapy safer and more effective by utilizing genetic patient data for drug dosing and selection. However, widespread adoption of PGx depends on its successful integration into routine clinical care through clinical decision support t...

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Autores principales: Blagec, Kathrin, Koopmann, Rudolf, Crommentuijn – van Rhenen, Mandy, Holsappel, Inge, van der Wouden, Cathelijne H, Konta, Lidija, Xu, Hong, Steinberger, Daniela, Just, Enrico, Swen, Jesse J, Guchelaar, Henk-Jan, Samwald, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016647/
https://www.ncbi.nlm.nih.gov/pubmed/29444243
http://dx.doi.org/10.1093/jamia/ocy005
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author Blagec, Kathrin
Koopmann, Rudolf
Crommentuijn – van Rhenen, Mandy
Holsappel, Inge
van der Wouden, Cathelijne H
Konta, Lidija
Xu, Hong
Steinberger, Daniela
Just, Enrico
Swen, Jesse J
Guchelaar, Henk-Jan
Samwald, Matthias
author_facet Blagec, Kathrin
Koopmann, Rudolf
Crommentuijn – van Rhenen, Mandy
Holsappel, Inge
van der Wouden, Cathelijne H
Konta, Lidija
Xu, Hong
Steinberger, Daniela
Just, Enrico
Swen, Jesse J
Guchelaar, Henk-Jan
Samwald, Matthias
author_sort Blagec, Kathrin
collection PubMed
description Clinical pharmacogenomics (PGx) has the potential to make pharmacotherapy safer and more effective by utilizing genetic patient data for drug dosing and selection. However, widespread adoption of PGx depends on its successful integration into routine clinical care through clinical decision support tools, which is often hampered by insufficient or fragmented infrastructures. This paper describes the setup and implementation of a unique multimodal, multilingual clinical decision support intervention consisting of digital, paper-, and mobile-based tools that are deployed across implementation sites in seven European countries participating in the Ubiquitous PGx (U-PGx) project.
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spelling pubmed-60166472018-07-05 Implementing pharmacogenomics decision support across seven European countries: The Ubiquitous Pharmacogenomics (U-PGx) project Blagec, Kathrin Koopmann, Rudolf Crommentuijn – van Rhenen, Mandy Holsappel, Inge van der Wouden, Cathelijne H Konta, Lidija Xu, Hong Steinberger, Daniela Just, Enrico Swen, Jesse J Guchelaar, Henk-Jan Samwald, Matthias J Am Med Inform Assoc Brief Communication Clinical pharmacogenomics (PGx) has the potential to make pharmacotherapy safer and more effective by utilizing genetic patient data for drug dosing and selection. However, widespread adoption of PGx depends on its successful integration into routine clinical care through clinical decision support tools, which is often hampered by insufficient or fragmented infrastructures. This paper describes the setup and implementation of a unique multimodal, multilingual clinical decision support intervention consisting of digital, paper-, and mobile-based tools that are deployed across implementation sites in seven European countries participating in the Ubiquitous PGx (U-PGx) project. Oxford University Press 2018-02-09 /pmc/articles/PMC6016647/ /pubmed/29444243 http://dx.doi.org/10.1093/jamia/ocy005 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of the American Medical Informatics Association. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Communication
Blagec, Kathrin
Koopmann, Rudolf
Crommentuijn – van Rhenen, Mandy
Holsappel, Inge
van der Wouden, Cathelijne H
Konta, Lidija
Xu, Hong
Steinberger, Daniela
Just, Enrico
Swen, Jesse J
Guchelaar, Henk-Jan
Samwald, Matthias
Implementing pharmacogenomics decision support across seven European countries: The Ubiquitous Pharmacogenomics (U-PGx) project
title Implementing pharmacogenomics decision support across seven European countries: The Ubiquitous Pharmacogenomics (U-PGx) project
title_full Implementing pharmacogenomics decision support across seven European countries: The Ubiquitous Pharmacogenomics (U-PGx) project
title_fullStr Implementing pharmacogenomics decision support across seven European countries: The Ubiquitous Pharmacogenomics (U-PGx) project
title_full_unstemmed Implementing pharmacogenomics decision support across seven European countries: The Ubiquitous Pharmacogenomics (U-PGx) project
title_short Implementing pharmacogenomics decision support across seven European countries: The Ubiquitous Pharmacogenomics (U-PGx) project
title_sort implementing pharmacogenomics decision support across seven european countries: the ubiquitous pharmacogenomics (u-pgx) project
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016647/
https://www.ncbi.nlm.nih.gov/pubmed/29444243
http://dx.doi.org/10.1093/jamia/ocy005
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