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Implementing pharmacogenomics decision support across seven European countries: The Ubiquitous Pharmacogenomics (U-PGx) project
Clinical pharmacogenomics (PGx) has the potential to make pharmacotherapy safer and more effective by utilizing genetic patient data for drug dosing and selection. However, widespread adoption of PGx depends on its successful integration into routine clinical care through clinical decision support t...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016647/ https://www.ncbi.nlm.nih.gov/pubmed/29444243 http://dx.doi.org/10.1093/jamia/ocy005 |
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author | Blagec, Kathrin Koopmann, Rudolf Crommentuijn – van Rhenen, Mandy Holsappel, Inge van der Wouden, Cathelijne H Konta, Lidija Xu, Hong Steinberger, Daniela Just, Enrico Swen, Jesse J Guchelaar, Henk-Jan Samwald, Matthias |
author_facet | Blagec, Kathrin Koopmann, Rudolf Crommentuijn – van Rhenen, Mandy Holsappel, Inge van der Wouden, Cathelijne H Konta, Lidija Xu, Hong Steinberger, Daniela Just, Enrico Swen, Jesse J Guchelaar, Henk-Jan Samwald, Matthias |
author_sort | Blagec, Kathrin |
collection | PubMed |
description | Clinical pharmacogenomics (PGx) has the potential to make pharmacotherapy safer and more effective by utilizing genetic patient data for drug dosing and selection. However, widespread adoption of PGx depends on its successful integration into routine clinical care through clinical decision support tools, which is often hampered by insufficient or fragmented infrastructures. This paper describes the setup and implementation of a unique multimodal, multilingual clinical decision support intervention consisting of digital, paper-, and mobile-based tools that are deployed across implementation sites in seven European countries participating in the Ubiquitous PGx (U-PGx) project. |
format | Online Article Text |
id | pubmed-6016647 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-60166472018-07-05 Implementing pharmacogenomics decision support across seven European countries: The Ubiquitous Pharmacogenomics (U-PGx) project Blagec, Kathrin Koopmann, Rudolf Crommentuijn – van Rhenen, Mandy Holsappel, Inge van der Wouden, Cathelijne H Konta, Lidija Xu, Hong Steinberger, Daniela Just, Enrico Swen, Jesse J Guchelaar, Henk-Jan Samwald, Matthias J Am Med Inform Assoc Brief Communication Clinical pharmacogenomics (PGx) has the potential to make pharmacotherapy safer and more effective by utilizing genetic patient data for drug dosing and selection. However, widespread adoption of PGx depends on its successful integration into routine clinical care through clinical decision support tools, which is often hampered by insufficient or fragmented infrastructures. This paper describes the setup and implementation of a unique multimodal, multilingual clinical decision support intervention consisting of digital, paper-, and mobile-based tools that are deployed across implementation sites in seven European countries participating in the Ubiquitous PGx (U-PGx) project. Oxford University Press 2018-02-09 /pmc/articles/PMC6016647/ /pubmed/29444243 http://dx.doi.org/10.1093/jamia/ocy005 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of the American Medical Informatics Association. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Brief Communication Blagec, Kathrin Koopmann, Rudolf Crommentuijn – van Rhenen, Mandy Holsappel, Inge van der Wouden, Cathelijne H Konta, Lidija Xu, Hong Steinberger, Daniela Just, Enrico Swen, Jesse J Guchelaar, Henk-Jan Samwald, Matthias Implementing pharmacogenomics decision support across seven European countries: The Ubiquitous Pharmacogenomics (U-PGx) project |
title | Implementing pharmacogenomics decision support across seven European countries: The Ubiquitous Pharmacogenomics (U-PGx) project |
title_full | Implementing pharmacogenomics decision support across seven European countries: The Ubiquitous Pharmacogenomics (U-PGx) project |
title_fullStr | Implementing pharmacogenomics decision support across seven European countries: The Ubiquitous Pharmacogenomics (U-PGx) project |
title_full_unstemmed | Implementing pharmacogenomics decision support across seven European countries: The Ubiquitous Pharmacogenomics (U-PGx) project |
title_short | Implementing pharmacogenomics decision support across seven European countries: The Ubiquitous Pharmacogenomics (U-PGx) project |
title_sort | implementing pharmacogenomics decision support across seven european countries: the ubiquitous pharmacogenomics (u-pgx) project |
topic | Brief Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016647/ https://www.ncbi.nlm.nih.gov/pubmed/29444243 http://dx.doi.org/10.1093/jamia/ocy005 |
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