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Flavoenzyme CrmK-mediated substrate recycling in caerulomycin biosynthesis

Substrate salvage or recycling is common and important for primary metabolism in cells but is rare in secondary metabolism. Herein we report flavoenzyme CrmK-mediated shunt product recycling in the biosynthesis of caerulomycin A (CRM A 1), a 2,2′-bipyridine-containing natural product that is under d...

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Detalles Bibliográficos
Autores principales:	Zhu, Yiguang, Picard, Marie-Ève, Zhang, Qingbo, Barma, Julie, Després, Xavier Murphy, Mei, Xiangui, Zhang, Liping, Duvignaud, Jean-Baptiste, Couture, Manon, Zhu, Weiming, Shi, Rong, Zhang, Changsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2016
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016722/ https://www.ncbi.nlm.nih.gov/pubmed/30155134 http://dx.doi.org/10.1039/c6sc00771f

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