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Mitochondrial dysfunction in down syndrome: molecular mechanisms and therapeutic targets
Trisomy of chromosome 21 (TS21) is the most common autosomal aneuploidy compatible with postnatal survival with a prevalence of 1 in 700 newborns. Its phenotype is highly complex with constant features, such as mental retardation, dysmorphic traits and hypotonia, and variable features including hear...
Autores principales: | Izzo, Antonella, Mollo, Nunzia, Nitti, Maria, Paladino, Simona, Calì, Gaetano, Genesio, Rita, Bonfiglio, Ferdinando, Cicatiello, Rita, Barbato, Maria, Sarnataro, Viviana, Conti, Anna, Nitsch, Lucio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016872/ https://www.ncbi.nlm.nih.gov/pubmed/30134785 http://dx.doi.org/10.1186/s10020-018-0004-y |
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