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Assessment of HIF-1α expression and release following endothelial injury in-vitro and in-vivo
BACKGROUND: Endothelial injury is an early and enduring feature of cardiovascular disease. Inflammation and hypoxia may be responsible for this, and are often associated with the up-regulation of several transcriptional factors that include Hypoxia Inducible Factor-1 (HIF-1). Although it has been re...
Autores principales: | Heikal, Lamia, Ghezzi, Pietro, Mengozzi, Manuela, Ferns, Gordon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016879/ https://www.ncbi.nlm.nih.gov/pubmed/30134815 http://dx.doi.org/10.1186/s10020-018-0026-5 |
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