Cargando…

Aloin Suppresses Lipopolysaccharide-Induced Inflammatory Response and Apoptosis by Inhibiting the Activation of NF-κB

Numerous herbal-derived natural products are excellent anti-inflammatory agents. Several studies have reported that aloin, the major anthraquinone glycoside obtained from the Aloe species, exhibits anti-inflammatory activity. However, the molecular mechanism of this activity is not well understood....

Descripción completa

Detalles Bibliográficos
Autores principales:	Luo, Xuan, Zhang, Haowei, Wei, Xiduan, Shi, Mengjuan, Fan, Ping, Xie, Weidong, Zhang, Yaou, Xu, Naihan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017010/ https://www.ncbi.nlm.nih.gov/pubmed/29495390 http://dx.doi.org/10.3390/molecules23030517

Ejemplares similares

Aloin in Pregnancy
por: Sircir, P. B.
Publicado: (1932)

On the Therapeutics of Aloin
por: Craig, William
Publicado: (1877)

MicroRNA-181a suppresses parkin-mediated mitophagy and sensitizes neuroblastoma cells to mitochondrial uncoupler-induced apoptosis
por: Cheng, Min, et al.
Publicado: (2016)

RNA-binding protein CELF6 is cell cycle regulated and controls cancer cell proliferation by stabilizing p21
por: Liu, Gang, et al.
Publicado: (2019)

Plasma, tissue and urinary levels of aloin in rats after the administration of pure aloin
por: Park, Mi-Young, et al.
Publicado: (2008)

Upregulation of GPNCA is associated with poor prognosis through enhancement of tumor growth via regulating GSK3B
por: Liao, Weijie, et al.
Publicado: (2020)

MBNL2 Regulates DNA Damage Response via Stabilizing p21
por: Cai, Jin, et al.
Publicado: (2021)

Aloin Regulates Matrix Metabolism and Apoptosis in Human Nucleus Pulposus Cells via the TAK1/NF-κB/NLRP3 Signaling Pathway
por: Chen, Taiqiu, et al.
Publicado: (2022)

On Aloin: The Cathartic Principle of the Aloes
Publicado: (1851)

Aloin suppresses lipopolysaccharide-induced inflammation by inhibiting JAK1-STAT1/3 activation and ROS production in RAW264.7 cells
por: Ma, Yunfei, et al.
Publicado: (2018)

Sandwich structure Aloin-PVP/Aloin-PVP-PLA/PLA as a wound dressing to accelerate wound healing
por: Li, Weiping, et al.
Publicado: (2022)

Notes on "Changed Aloin" and the Resin of Aloes
por: Craig, William
Publicado: (1875)

Notes on "Changed Aloin" and the Resin of Aloes
por: Craig, William
Publicado: (1875)

RNA-binding Protein MBNL2 regulates Cancer Cell Metastasis through MiR-182-MBNL2-AKT Pathway
por: Lin, Guanglan, et al.
Publicado: (2021)

Evaluation of anti-infective potencies of formulated aloin A ointment and aloin A isolated from Aloe barbadensis Miller
por: Donkor, Addai-Mensah, et al.
Publicado: (2020)

SIRT7 Regulates Lipopolysaccharide-Induced Inflammatory Injury by Suppressing the NF-κB Signaling Pathway
por: Chen, Kun-Lin, et al.
Publicado: (2019)

Persistent high glucose induced EPB41L4A‐AS1 inhibits glucose uptake via GCN5 mediating crotonylation and acetylation of histones and non‐histones
por: Liao, Weijie, et al.
Publicado: (2022)

Aloin induced apoptosis by enhancing autophagic flux through the PI3K/AKT axis in osteosarcoma
por: He, Jiaming, et al.
Publicado: (2021)

Upregulation of the APOBEC3 Family Is Associated with a Poor Prognosis and Influences Treatment Response to Raf Inhibitors in Low Grade Glioma
por: Luo, Cheng, et al.
Publicado: (2021)

Papaverine inhibits lipopolysaccharide-induced microglial activation by suppressing NF-κB signaling pathway
por: Dang, Yalong, et al.
Publicado: (2016)

Schisandra Chinensis Lignans Suppresses the Production of Inflammatory Mediators Regulated by NF-κB, AP-1, and IRF3 in Lipopolysaccharide-Stimulated RAW264.7 Cells
por: Luo, Gan, et al.
Publicado: (2018)

MicroRNA-188 suppresses G(1)/S transition by targeting multiple cyclin/CDK complexes
por: Wu, Jiangbin, et al.
Publicado: (2014)

Aloin promotes cell apoptosis by targeting HMGB1-TLR4-ERK axis in human melanoma cells
por: Li, Pan, et al.
Publicado: (2020)

The molecular mechanisms of Aloin induce gastric cancer cells apoptosis by targeting High Mobility Group Box 1
por: Tao, Hong, et al.
Publicado: (2019)

Aloin Preconditioning Attenuates Hepatic Ischemia/Reperfusion Injury via Inhibiting TLR4/MyD88/NF-κB Signal Pathway In Vivo and In Vitro
por: Du, Yichao, et al.
Publicado: (2019)

Baicalin Alleviates Lipopolysaccharide-Induced Liver Inflammation in Chicken by Suppressing TLR4-Mediated NF-κB Pathway
por: Cheng, Ping, et al.
Publicado: (2017)

Canagliflozin attenuates lipotoxicity in cardiomyocytes and protects diabetic mouse hearts by inhibiting the mTOR/HIF-1α pathway
por: Sun, Pengbo, et al.
Publicado: (2021)

miR-181a Regulates Inflammation Responses in Monocytes and Macrophages
por: Xie, Weidong, et al.
Publicado: (2013)

Luteolin Suppresses Inflammatory Mediator Expression by Blocking the Akt/NFκB Pathway in Acute Lung Injury Induced by Lipopolysaccharide in Mice
por: Li, Yi-Ching, et al.
Publicado: (2012)

Anti-Inflammatory Effect of Mangostenone F in Lipopolysaccharide-Stimulated RAW264.7 Macrophages by Suppressing NF-κB and MAPK Activation
por: Cho, Byoung Ok, et al.
Publicado: (2014)

Salicortin suppresses lipopolysaccharide-stimulated inflammatory responses via blockade of NF-κB and JNK activation in RAW 264.7 macrophages
por: Kwon, Dong-Joo, et al.
Publicado: (2014)

Inhibition of the angiogenesis and growth of Aloin in human colorectal cancer in vitro and in vivo
por: Pan, Qin, et al.
Publicado: (2013)

Canagliflozin Delays Aging of HUVECs Induced by Palmitic Acid via the ROS/p38/JNK Pathway
por: Hao, Wenhui, et al.
Publicado: (2023)

Canagliflozin Attenuates Lipotoxicity in Cardiomyocytes by Inhibiting Inflammation and Ferroptosis through Activating AMPK Pathway
por: Zhang, Wanqiu, et al.
Publicado: (2023)

SQSTM1/p62 Knockout by Using the CRISPR/Cas9 System Inhibits Migration and Invasion of Hepatocellular Carcinoma
por: Lu, Jinghua, et al.
Publicado: (2023)

Anthocyanins Downregulate Lipopolysaccharide-Induced Inflammatory Responses in BV2 Microglial Cells by Suppressing the NF-κB and Akt/MAPKs Signaling Pathways
por: Jeong, Jin-Woo, et al.
Publicado: (2013)

Chlojaponilactone B Attenuates Lipopolysaccharide-Induced Inflammatory Responses by Suppressing TLR4-Mediated ROS Generation and NF-κB Signaling Pathway
por: Ye, Shaoxia, et al.
Publicado: (2019)

Quercetin Alleviates Lipopolysaccharide-Induced Inflammatory Response in Bovine Mammary Epithelial Cells by Suppressing TLR4/NF-κB Signaling Pathway
por: Jiang, Maocheng, et al.
Publicado: (2022)

Integrating Network Pharmacology and Experimental Verification to Explore the Pharmacological Mechanisms of Aloin Against Gastric Cancer
por: Gao, Jia, et al.
Publicado: (2022)

Toddalolactone Protects Lipopolysaccharide-Induced Sepsis and Attenuates Lipopolysaccharide-Induced Inflammatory Response by Modulating HMGB1-NF-κB Translocation
por: Ni, Jingyu, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_7186auoqq69tbelunblpce52pe