The Reaction of Oxy Hemoglobin with Nitrite: Mechanism, Antioxidant-Modulated Effect, and Implications for Blood Substitute Evaluation

The autocatalytic reaction between nitrite and the oxy form of globins involves free radicals. For myoglobin (Mb), an initial binding of nitrite to the iron-coordinated oxygen molecule was proposed; the resulting ferrous-peroxynitrate species was not detected, but its decay product, the high-valent...

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Detalles Bibliográficos
Autores principales: Hathazi, Denisa, Scurtu, Florina, Bischin, Cristina, Mot, Augustin, Attia, Amr A. A., Kongsted, Jacob, Silaghi-Dumitrescu, Radu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017026/
https://www.ncbi.nlm.nih.gov/pubmed/29414908
http://dx.doi.org/10.3390/molecules23020350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017026/
https://www.ncbi.nlm.nih.gov/pubmed/29414908
http://dx.doi.org/10.3390/molecules23020350

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