Cargando…

Investigation of Absorption Routes of Meloxicam and Its Salt Form from Intranasal Delivery Systems

The aim of this article was to study the trans-epithelial absorption to reach the blood and to target the brain by axonal transport using nasal formulations with nanonized meloxicam (nano MEL spray) and its salt form known as meloxicam potassium monohydrate (MELP spray). The physicochemical properti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bartos, Csilla, Ambrus, Rita, Kovács, Anita, Gáspár, Róbert, Sztojkov-Ivanov, Anita, Márki, Árpád, Janáky, Tamás, Tömösi, Ferenc, Kecskeméti, Gábor, Szabó-Révész, Piroska
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017030/ https://www.ncbi.nlm.nih.gov/pubmed/29597330 http://dx.doi.org/10.3390/molecules23040784

Ejemplares similares

Investigation of the Absorption of Nanosized lamotrigine Containing Nasal Powder via the Nasal Cavity
por: Ambrus, Rita, et al.
Publicado: (2020)

Transformation of Meloxicam Containing Nanosuspension into Surfactant-Free Solid Compositions to Increase the Product Stability and Drug Bioavailability for Rapid Analgesia
por: Bartos, Csaba, et al.
Publicado: (2019)

Development of Meloxicam-Human Serum Albumin Nanoparticles for Nose-to-Brain Delivery via Application of a Quality by Design Approach
por: Katona, Gábor, et al.
Publicado: (2020)

Formulation and In Vitro and In Silico Characterization of “Nano-in-Micro” Dry Powder Inhalers Containing Meloxicam
por: Party, Petra, et al.
Publicado: (2021)

Smartcrystals for Efficient Dissolution of Poorly Water-Soluble Meloxicam
por: Ambrus, Rita, et al.
Publicado: (2022)

Physico-Chemical, In Vitro and Ex Vivo Characterization of Meloxicam Potassium-Cyclodextrin Nanospheres
por: Varga, Patrícia, et al.
Publicado: (2021)

The Effect of an Optimized Wet Milling Technology on the Crystallinity, Morphology and Dissolution Properties of Micro- and Nanonized Meloxicam
por: Bartos, Csilla, et al.
Publicado: (2016)

Development of an Innovative, Carrier-Based Dry Powder Inhalation Formulation Containing Spray-Dried Meloxicam Potassium to Improve the In Vitro and In Silico Aerodynamic Properties
por: Benke, Edit, et al.
Publicado: (2020)

Comparison of Modern In Vitro Permeability Methods with the Aim of Investigation Nasal Dosage Forms
por: Bartos, Csilla, et al.
Publicado: (2021)

Physico-Chemical and In Vitro Characterization of Chitosan-Based Microspheres Intended for Nasal Administration
por: Bartos, Csilla, et al.
Publicado: (2021)

Quality by Design Based Formulation Study of Meloxicam-Loaded Polymeric Micelles for Intranasal Administration
por: Sipos, Bence, et al.
Publicado: (2020)

Fabrication of Submicrometer-Sized Meloxicam Particles Using Femtosecond Laser Ablation in Gas and Liquid Environments
por: Nagy, Eszter, et al.
Publicado: (2021)

A comparative study of femtosecond pulsed laser ablation of meloxicam in distilled water and in air
por: Nagy, Eszter, et al.
Publicado: (2023)

A comprehensive analysis of meloxicam particles produced by nanosecond laser ablation as a wet milling technique
por: Nagy, Eszter, et al.
Publicado: (2022)

Cytotoxicity of Different Excipients on RPMI 2650 Human Nasal Epithelial Cells
por: Horváth, Tamás, et al.
Publicado: (2016)

The Development of an In Vitro Horizontal Diffusion Cell to Monitor Nasal Powder Penetration Inline
por: Gieszinger, Péter, et al.
Publicado: (2021)

Clinical relevance of depressed kynurenine pathway in episodic migraine patients: potential prognostic markers in the peripheral plasma during the interictal period
por: Tuka, Bernadett, et al.
Publicado: (2021)

A Novel Murine Model for the In Vivo Study of Transdermal Drug Penetration
por: Erős, Gábor, et al.
Publicado: (2012)

Rheological effects of hypertonic saline and sodium bicarbonate solutions on cystic fibrosis sputum in vitro
por: Budai-Szűcs, Mária, et al.
Publicado: (2021)

Stability and In Vitro Aerodynamic Studies of Inhalation Powders Containing Ciprofloxacin Hydrochloride Applying Different DPI Capsule Types
por: Benke, Edit, et al.
Publicado: (2021)

Development of In Situ Gelling Meloxicam-Human Serum Albumin Nanoparticle Formulation for Nose-to-Brain Application
por: Katona, Gábor, et al.
Publicado: (2021)

An Extensive Study of Phenol Red Thread as a Novel Non-Invasive Tear Sampling Technique for Proteomics Studies: Comparison with Two Commonly Used Methods
por: Kecskeméti, Gábor, et al.
Publicado: (2022)

Preparation and Characterization of Ibuprofen Containing Nano-Embedded-Microparticles for Pulmonary Delivery
por: Party, Petra, et al.
Publicado: (2023)

Development of a microparticle-based dry powder inhalation formulation of ciprofloxacin hydrochloride applying the quality by design approach
por: Karimi, Keyhaneh, et al.
Publicado: (2016)

The effect of ethanol on the habit and in vitro aerodynamic results of dry powder inhalation formulations containing ciprofloxacin hydrochloride
por: Benke, Edit, et al.
Publicado: (2021)

Characterizing the Drug-Release Enhancement Effect of Surfactants on Megestrol-Acetate-Loaded Granules
por: Katona, Gábor, et al.
Publicado: (2022)

Cluster headache and kynurenines
por: Tuka, Bernadett, et al.
Publicado: (2023)

Indoleamine 2,3-Dioxygenase Cannot Inhibit Chlamydia trachomatis Growth in HL-60 Human Neutrophil Granulocytes
por: Virok, Dezső P., et al.
Publicado: (2021)

Aronia Berry Processing by Spray Drying: From Byproduct to High Quality Functional Powder
por: Vidović, Senka, et al.
Publicado: (2019)

Optimization of a combined wet milling process in order to produce poly(vinyl alcohol) stabilized nanosuspension
por: Bartos, Csaba, et al.
Publicado: (2018)

In Vitro Drug Release, Permeability, and Structural Test of Ciprofloxacin-Loaded Nanofibers
por: Uhljar, Luca Éva, et al.
Publicado: (2021)

Application of pulsed laser ablation (PLA) for the size reduction of non-steroidal anti-inflammatory drugs (NSAIDs)
por: Gera, Tamás, et al.
Publicado: (2020)

Preliminary study of nanonized lamotrigine containing products for nasal powder formulation
por: Gieszinger, Péter, et al.
Publicado: (2017)

High Fat High Sucrose Diet Modifies Uterine Contractility and Cervical Resistance in Pregnant Rats: The Roles of Sex Hormones, Adipokines and Cytokines
por: Gáspár, Róbert, et al.
Publicado: (2022)

Effects of sub-chronic, in vivo administration of sigma-1 receptor ligands on platelet and aortic arachidonate cascade in streptozotocin-induced diabetic rats
por: Váczi, Sándor, et al.
Publicado: (2022)

Spray Drying of a Subcritical Extract Using Marrubium vulgare as a Method of Choice for Obtaining High Quality Powder
por: Gavarić, Aleksandra, et al.
Publicado: (2019)

Development of Solvent-Free Co-Ground Method to Produce Terbinafine Hydrochloride Cyclodextrin Binary Systems; Structural and In Vitro Characterizations
por: Kondoros, Balázs Attila, et al.
Publicado: (2022)

Dipyridamole-Induced Left Ventricular “Rigid Body Rotation” (A Case from the Three-Dimensional Speckle Tracking Echocardiographic MAGYAR-Stress Study)
por: Nemes, Attila, et al.
Publicado: (2019)

Normal reference values of right atrial strain parameters using three-dimensional speckle-tracking echocardiography (results from the MAGYAR-Healthy Study)
por: Nemes, Attila, et al.
Publicado: (2019)

Meloxicam-Induced Pancreatitis
por: Landa, Eric, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_qs671rc5534h9kuh1d99631dpr