Two Novel Cycloartane-Type Triterpenes from Trichilia casaretti C. DC. (Meliaceae)

Two new triterpenes cycloartane-type, named 24-methylencycloartan-12-oxo-3β,22α-diol and trichiliol, were isolated from the leaves of Trichilia casaretti C. DC. together with three known triterpenes—24-methylencycloart-3β,22-diol, 22,25-dihydrocycloart-23(E)-en-3β-ol, and 22(R)-hydroxycycloart-24-en...

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Detalles Bibliográficos
Autores principales: Vieira, Ivo Jose Curcino, Figueiredo, Elaine Rodrigues, Vieira, Milena Gonçalves Curcino, de Carvalho Junior, Almir Ribeiro, Passos, Michel de Souza, Boeno, Samyra Imad da Silva, Azevedo, Otoniel Aquino, Braz-Filho, Raimundo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017113/
https://www.ncbi.nlm.nih.gov/pubmed/29671765
http://dx.doi.org/10.3390/molecules23040949
Descripción
Sumario:Two new triterpenes cycloartane-type, named 24-methylencycloartan-12-oxo-3β,22α-diol and trichiliol, were isolated from the leaves of Trichilia casaretti C. DC. together with three known triterpenes—24-methylencycloart-3β,22-diol, 22,25-dihydrocycloart-23(E)-en-3β-ol, and 22(R)-hydroxycycloart-24-en-3-ol. These compounds were characterized on the basis of their spectral data, mainly 1D ((1)H and (13)C) and 2D NMR ((1)H-(1)H-COSY, (1)H-(1)H-NOESY, HMQC, HSQC, and HMBC), and mass spectra (EI-MS and HR-ESI-MS), also involving comparison with data from the literature.

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