Cargando…

Synthesis and Antiproliferative Activity of Minor Hops Prenylflavonoids and New Insights on Prenyl Group Cyclization

Synthesis of minor prenylflavonoids found in hops and their non-natural derivatives were performed. The antiproliferative activity of the obtained compounds against some human cancer cell lines was investigated. Using xanthohumol isolated from spent hops as a lead compound, a series of minor hop pre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Popłoński, Jarosław, Turlej, Eliza, Sordon, Sandra, Tronina, Tomasz, Bartmańska, Agnieszka, Wietrzyk, Joanna, Huszcza, Ewa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017146/ https://www.ncbi.nlm.nih.gov/pubmed/29597299 http://dx.doi.org/10.3390/molecules23040776

Ejemplares similares

Prenylated Flavonoids with Selective Toxicity against Human Cancers
por: Tronina, Tomasz, et al.
Publicado: (2023)

Highly Cancer Selective Antiproliferative Activity of Natural Prenylated Flavonoids
por: Bartmańska, Agnieszka, et al.
Publicado: (2018)

The Influence of Glycosylation of Natural and Synthetic Prenylated Flavonoids on Binding to Human Serum Albumin and Inhibition of Cyclooxygenases COX-1 and COX-2
por: Tronina, Tomasz, et al.
Publicado: (2017)

Antimicrobial Properties of Spent Hops Extracts, Flavonoids Isolated Therefrom, and Their Derivatives
por: Bartmańska, Agnieszka, et al.
Publicado: (2018)

Simple and Rapid Method for Wogonin Preparation and Its Biotransformation
por: Tronina, Tomasz, et al.
Publicado: (2021)

Structure–Antioxidant–Antiproliferative Activity Relationships of Natural C7 and C7–C8 Hydroxylated Flavones and Flavanones
por: Sordon, Sandra, et al.
Publicado: (2019)

Flavonoids as Phytoestrogenic Components of Hops and Beer
por: Tronina, Tomasz, et al.
Publicado: (2020)

Microbial Glycosylation of Daidzein, Genistein and Biochanin A: Two New Glucosides of Biochanin A
por: Sordon, Sandra, et al.
Publicado: (2017)

Novel flavonoid C-8 hydroxylase from Rhodotorula glutinis: identification, characterization and substrate scope
por: Dulak, Kinga, et al.
Publicado: (2022)

Evaluation of double expression system for co-expression and co-immobilization of flavonoid glucosylation cascade
por: Matera, Agata, et al.
Publicado: (2022)

Antiproliferative Effects of Hop-derived Prenylflavonoids and Their Influence on the Efficacy of Oxaliplatine, 5-fluorouracil and Irinotecan in Human ColorectalC Cells
por: Ambrož, Martin, et al.
Publicado: (2019)

The Effect of Xanthohumol Derivatives on Apoptosis Induction in Canine Lymphoma and Leukemia Cell Lines
por: Grudzień, Małgorzata, et al.
Publicado: (2023)

Improved Oxidation of Naringenin to Carthamidin and Isocarthamidin by Rhodotorula marina
por: Madej, Anna, et al.
Publicado: (2014)

Inhibition of Osteoclastogenesis and Bone Resorption in vitro and in vivo by a prenylflavonoid xanthohumol from hops
por: Li, Jing, et al.
Publicado: (2015)

Antiproliferative Activity and in Vivo Toxicity of Double-Point Modified Analogs of 1,25-Dihydroxyergocalciferol
por: Trynda, Justyna, et al.
Publicado: (2015)

The Antioxidant Activity of Prenylflavonoids
por: Santos, Clementina M. M., et al.
Publicado: (2020)

The Modulation of Phase II Drug-Metabolizing Enzymes in Proliferating and Differentiated CaCo-2 Cells by Hop-Derived Prenylflavonoids
por: Lněničková, Kateřina, et al.
Publicado: (2020)

Bioactivity In Vitro of Quercetin Glycoside Obtained in Beauveria bassiana Culture and Its Interaction with Liposome Membranes
por: Strugała, Paulina, et al.
Publicado: (2017)

Antioxidant activities of licorice-derived prenylflavonoids
por: Kim, Hyo Jung, et al.
Publicado: (2012)

Stable Isotope Dilution Analysis of the Major Prenylated Flavonoids Found in Beer, Hop Tea, and Hops
por: Buckett, Lance, et al.
Publicado: (2020)

Anti-obesity effect of a hop-derived prenylflavonoid isoxanthohumol in a high-fat diet-induced obese mouse model
por: FUKIZAWA, Shinya, et al.
Publicado: (2020)

Golden Standard: a complete standard, portable, and interoperative MoClo tool for model and non-model proteobacteria
por: Blázquez, Blas, et al.
Publicado: (2023)

Similarities and differences in d(6) low-spin ruthenium, rhodium and iridium half-sandwich complexes: synthesis, structure, cytotoxicity and interaction with biological targets
por: Gilewska, Agnieszka, et al.
Publicado: (2019)

Biotransformation of Methoxyflavones by Selected Entomopathogenic Filamentous Fungi
por: Łużny, Mateusz, et al.
Publicado: (2020)

Pharmacological Profile of Xanthohumol, a Prenylated Flavonoid from Hops (Humulus lupulus)
por: Liu, Ming, et al.
Publicado: (2015)

Octahydroquinoxalin-2(1H)-One-Based Aminophosphonic Acids and Their Derivatives—Biological Activity towards Cancer Cells
por: Iwanejko, Jakub, et al.
Publicado: (2020)

Synthesis and Anticancer Evaluation of Novel Derivatives of Isoxazolo[4,5-e][1,2,4]triazepine Derivatives and Potential Inhibitors of Protein Kinase C
por: Wagner, Edwin, et al.
Publicado: (2020)

The Impact of Exosomes/Microvesicles Derived from Myeloid Dendritic Cells Cultured in the Presence of Calcitriol and Tacalcitol on Acute B-Cell Precursor Cell Lines with MLL Fusion Gene
por: Turlej, Eliza, et al.
Publicado: (2022)

Effects and Mechanisms of Five Psoralea Prenylflavonoids on Aging-Related Diseases
por: Zhou, Yi-Ting, et al.
Publicado: (2020)

Anticancer Activity and Mechanism of Xanthohumol: A Prenylated Flavonoid From Hops (Humulus lupulus L.)
por: Jiang, Chuan-Hao, et al.
Publicado: (2018)

Xanthohumol, a Prenylated Chalcone Derived from Hops, Inhibits Growth and Metastasis of Melanoma Cells
por: Seitz, Tatjana, et al.
Publicado: (2021)

Synthesis of Human Phase I and Phase II Metabolites of Hop (Humulus lupulus) Prenylated Flavonoids
por: Buckett, Lance, et al.
Publicado: (2022)

Minor Prenylated Flavonoids from the Twigs of Macarangaadenantha and Their Cytotoxic Activity
por: Yang, Da-Song, et al.
Publicado: (2015)

Synthesis and Antiproliferative Screening Of Novel Analogs of Regioselectively Demethylated Colchicine and Thiocolchicine
por: Czerwonka, Dominika, et al.
Publicado: (2020)

Synthesis and in vitro antiproliferative activity of novel (4-chloro- and 4-acyloxy-2-butynyl)thioquinolines
por: Boryczka, Stanisław, et al.
Publicado: (2010)

Xanthohumol, a Prenylated Flavonoid from Hops (Humulus lupulus), Prevents Platelet Activation in Human Platelets
por: Lee, Ye-Ming, et al.
Publicado: (2012)

Xanthohumol, a prenylated flavonoid from Hops, exerts anticancer effects against gastric cancer in vitro
por: Wei, Shanshan, et al.
Publicado: (2018)

Effect of drying processes on prenylflavonoid content and antioxidant activity of Epimedium koreanum Nakai
por: Zhao, Yudan, et al.
Publicado: (2017)

Synthesis and Antiproliferative Activity of Triazoles Based on 2-Azabicycloalkanes
por: Steppeler, Franz, et al.
Publicado: (2021)

Micro-RNAs in Response to Active Forms of Vitamin D(3) in Human Leukemia and Lymphoma Cells
por: Gleba, Justyna Joanna, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_eb57d9bkghtjor8jkdb0mtltbd