Cargando…

Anticonvulsant Activity of Halogen-Substituted Cinnamic Acid Derivatives and Their Effects on Glycosylation of PTZ-Induced Chronic Epilepsy in Mice

Epilepsy is a common chronic neurological disorder disease, and there is an urgent need for the development of novel anticonvulsant drugs. In this study, the anticonvulsant activities and neurotoxicity of 12 cinnamic acid derivatives substituted by fluorine, chlorine, bromine, and trifluoromethyl gr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cuan, Ye, He, Xirui, Zhao, Yuhui, Yang, Jiajun, Bai, Yajun, Sun, Yin, Zhang, Qiang, Zhao, Zefeng, Wei, Xiaoyang, Zheng, Xiaohui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017195/ https://www.ncbi.nlm.nih.gov/pubmed/29286347 http://dx.doi.org/10.3390/molecules23010076

Ejemplares similares

Anticonvulsant Activity of Teucrium polium Against Seizure Induced by PTZ and MES in Mice
por: Khoshnood-Mansoorkhani, Mohammad Javad, et al.
Publicado: (2010)

Novel derivatives of phthalimide with potent anticonvulsant activity in PTZ and MES seizure models
por: Davood, Asghar, et al.
Publicado: (2017)

NMDA Receptor Mediates the Anticonvulsant Effect of Hydroalcoholic Extract of Artemisia persica in PTZ-Induced Seizure in Mice
por: Nasiri-Boroujeni, Shakiba, et al.
Publicado: (2021)

Substitution of anticonvulsant drugs
por: Steinhoff, Bernhard J, et al.
Publicado: (2009)

Pregnancy, epilepsy, and anticonvulsants
por: Steinhoff, Bernhard J
Publicado: (2008)

Phytochemistry, Pharmacology and Traditional Uses of Plants from the Genus Trachelospermum L.
por: Zhao, Zefeng, et al.
Publicado: (2017)

Anticonvulsive Effects and Pharmacokinetic Profile of Cannabidiol (CBD) in the Pentylenetetrazol (PTZ) or N-Methyl-D-Aspartate (NMDA) Models of Seizures in Infantile Rats
por: Uttl, Libor, et al.
Publicado: (2021)

Increased ACh-Associated Immunoreactivity in Autonomic Centers in PTZ Kindling Model of Epilepsy
por: Akyüz, Enes, et al.
Publicado: (2020)

Anticonvulsant-induced downbeat nystagmus in epilepsy
por: Wu, Dongyan, et al.
Publicado: (2015)

Role of Anticonvulsants in the Management of Posttraumatic Epilepsy
por: Kirmani, Batool F., et al.
Publicado: (2016)

Staged anticonvulsant screening for chronic epilepsy
por: Berdichevsky, Yevgeny, et al.
Publicado: (2016)

Cannabidivarin (CBDV) suppresses pentylenetetrazole (PTZ)-induced increases in epilepsy-related gene expression
por: Amada, Naoki, et al.
Publicado: (2013)

The Brain Protein Acylation System Responds to Seizures in the Rat Model of PTZ-Induced Epilepsy
por: Zavileyskiy, Lev G., et al.
Publicado: (2022)

Improved Stage Categorization of PTZ-Induced Kindling and Late Enhanced Neurogenesis in PTZ Kindled Mice
por: Shahpari, Marzieh, et al.
Publicado: (2019)

The Potential Mechanism of Cannabidiol (CBD) Treatment of Epilepsy in Pentetrazol (PTZ) Kindling Mice Uncovered by Multi-Omics Analysis
por: Lu, Hongyuan, et al.
Publicado: (2023)

Distal meta-C–H functionalization of α-substituted cinnamates
por: Bakthadoss, Manickam, et al.
Publicado: (2023)

Correction: Sun, Y.; et al. Design, Synthesis, and Evaluation of Novel 2-Hydroxypyrrolobenzodiazepine-5,11-dione Analogues as Potent Angiotensin Converting Enzyme (ACE) Inhibitors. Molecules 2017, 22, 1739
por: Sun, Ying, et al.
Publicado: (2018)

Design, Synthesis, and Evaluation of Novel Phenolic Acid/Dipeptide/Borneol Hybrids as Potent Angiotensin Converting Enzyme (ACE) Inhibitors with Anti-hypertension Activity
por: Sun, Ying, et al.
Publicado: (2017)

Role of Anticonvulsant and Antiepileptogenic Neurosteroids in the Pathophysiology and Treatment of Epilepsy
por: Reddy, Doodipala Samba
Publicado: (2011)

Anticonvulsant Essential Oils and Their Relationship with Oxidative Stress in Epilepsy
por: da Fonsêca, Diogo Vilar, et al.
Publicado: (2019)

Mechanochemical halogenation of unsymmetrically substituted azobenzenes
por: Barišić, Dajana, et al.
Publicado: (2022)

Antiepileptic potential of Bacopa monnieri in the rat brain during PTZ-induced epilepsy with reference to cholinergic system and ATPases
por: Komali, E., et al.
Publicado: (2020)

Screening of conventional anticonvulsants in a genetic mouse model of epilepsy
por: Hawkins, Nicole A., et al.
Publicado: (2017)

Creatininium cinnamate
por: Ali, A. Jahubar, et al.
Publicado: (2011)

Neuronal Nitric Oxide Synthase Contributes to PTZ Kindling Epilepsy-Induced Hippocampal Endoplasmic Reticulum Stress and Oxidative Damage
por: Zhu, Xinjian, et al.
Publicado: (2017)

Evaluation of the Anticonvulsant Effect of Brilliant Blue G, a Selective P2X7 Receptor Antagonist, in the iv PTZ-, Maximal Electroshock-, and 6 Hz-Induced Seizure Tests in Mice
por: Nieoczym, Dorota, et al.
Publicado: (2017)

Anticonvulsant activity of Erythrina mysorensis bark extract in an animal model of epilepsy
por: Nagaraja, T. S., et al.
Publicado: (2012)

SAD-B modulates epileptic seizure by regulating AMPA receptors in patients with temporal lobe epilepsy and in the PTZ-induced epileptic model
por: Li, Rong, et al.
Publicado: (2020)

Effect of Various Antiepileptic Drugs in Zebrafish PTZ-Seizure Model
por: Gupta, P., et al.
Publicado: (2014)

Naturally Occurring Cinnamic Acid Sugar Ester Derivatives
por: Tian, Yuxin, et al.
Publicado: (2016)

Docking, Synthesis and Anticonvulsant Activity of N-substituted Isoindoline-1,3-dione
por: Iman, Maryam, et al.
Publicado: (2017)

Design, Synthesis and Anticancer Evaluation of Substituted Cinnamic Acid Bearing 2-Quinolone Hybrid Derivatives
por: Abu Almaaty, Ali H., et al.
Publicado: (2021)

The Anticonvulsant and Antioxidant Effects of Berberine in Kainate-induced Temporal Lobe Epilepsy in Rats
por: Mojarad, Tourandokht Baluchnejad, et al.
Publicado: (2014)

Ameliorative Effect of Ethanolic Extract of Moringa oleifera Leaves in Combination with Curcumin against PTZ-Induced Kindled Epilepsy in Rats: In Vivo and In Silico
por: Alam, Md. Niyaz, et al.
Publicado: (2023)

Interference of TRPV1 function altered the susceptibility of PTZ-induced seizures
por: Jia, Yun-Fang, et al.
Publicado: (2015)

Cinnamate-based DNA photolithography
por: Feng, Lang, et al.
Publicado: (2013)

Multifunctional Cinnamic Acid Derivatives
por: Peperidou, Aikaterini, et al.
Publicado: (2017)

Design and Synthesis of Some Novel 4-(4-substituted aryl) Semicarbazones as Anticonvulsant Agents
por: Singh, Anita, et al.
Publicado: (2010)

Photoredox Catalyzed Dealkylative Aromatic Halogen Substitution with Tertiary Amines
por: Lipilin, Dmitry L., et al.
Publicado: (2021)

Garcinol Upregulates GABA(A) and GAD65 Expression, Modulates BDNF-TrkB Pathway to Reduce Seizures in Pentylenetetrazole (PTZ)-Induced Epilepsy
por: Hao, Fang, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_uudhd2lmce1h47n03li4c7uq9f