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Fucoxanthin and Polyunsaturated Fatty Acids Co-Extraction by a Green Process

By their autotrophic nature and their molecular richness, microalgae are serious assets in the context of current environmental and societal challenges. Some species produce both omega-3 long chain polyunsaturated fatty acids (PUFAs) and xanthophylls, two molecular families widely studied for their...

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Autores principales: Delbrut, Antoine, Albina, Pierre, Lapierre, Théo, Pradelles, Rémi, Dubreucq, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017215/
https://www.ncbi.nlm.nih.gov/pubmed/29641444
http://dx.doi.org/10.3390/molecules23040874
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author Delbrut, Antoine
Albina, Pierre
Lapierre, Théo
Pradelles, Rémi
Dubreucq, Eric
author_facet Delbrut, Antoine
Albina, Pierre
Lapierre, Théo
Pradelles, Rémi
Dubreucq, Eric
author_sort Delbrut, Antoine
collection PubMed
description By their autotrophic nature and their molecular richness, microalgae are serious assets in the context of current environmental and societal challenges. Some species produce both omega-3 long chain polyunsaturated fatty acids (PUFAs) and xanthophylls, two molecular families widely studied for their bioactivities in the fields of nutrition and cosmetics. Whereas most studies separately deal with the two families, synergies could be exploited with extracts containing both PUFAs and xanthophylls. The purpose of our work was to determine cost effective and eco-friendly parameters for their co-extraction. The effect of several parameters (solvent, solvent/biomass ratio, temperature, duration) were studied, using two microalgal species, the non-calcifying Haptophyta Tisochrysis lutea, and the diatom Phaeodactylum tricornutum, that presents a silicified frustule. Analyses of PUFAs and fucoxanthin (Fx), the main xanthophyll, allowed to compare kinetics and extraction yields between experimental protocols. Co-extraction yields achieved using 96% ethanol as solvent were 100% for Fx and docosahexaenoic acid (DHA) in one hour from T. lutea biomass, and respectively 95% and 89% for Fx and eicosapentaenoic acid (EPA) in eight hours from P. tricornutum. These conditions are compatible with industrial applications.
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spelling pubmed-60172152018-11-13 Fucoxanthin and Polyunsaturated Fatty Acids Co-Extraction by a Green Process Delbrut, Antoine Albina, Pierre Lapierre, Théo Pradelles, Rémi Dubreucq, Eric Molecules Article By their autotrophic nature and their molecular richness, microalgae are serious assets in the context of current environmental and societal challenges. Some species produce both omega-3 long chain polyunsaturated fatty acids (PUFAs) and xanthophylls, two molecular families widely studied for their bioactivities in the fields of nutrition and cosmetics. Whereas most studies separately deal with the two families, synergies could be exploited with extracts containing both PUFAs and xanthophylls. The purpose of our work was to determine cost effective and eco-friendly parameters for their co-extraction. The effect of several parameters (solvent, solvent/biomass ratio, temperature, duration) were studied, using two microalgal species, the non-calcifying Haptophyta Tisochrysis lutea, and the diatom Phaeodactylum tricornutum, that presents a silicified frustule. Analyses of PUFAs and fucoxanthin (Fx), the main xanthophyll, allowed to compare kinetics and extraction yields between experimental protocols. Co-extraction yields achieved using 96% ethanol as solvent were 100% for Fx and docosahexaenoic acid (DHA) in one hour from T. lutea biomass, and respectively 95% and 89% for Fx and eicosapentaenoic acid (EPA) in eight hours from P. tricornutum. These conditions are compatible with industrial applications. MDPI 2018-04-11 /pmc/articles/PMC6017215/ /pubmed/29641444 http://dx.doi.org/10.3390/molecules23040874 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Delbrut, Antoine
Albina, Pierre
Lapierre, Théo
Pradelles, Rémi
Dubreucq, Eric
Fucoxanthin and Polyunsaturated Fatty Acids Co-Extraction by a Green Process
title Fucoxanthin and Polyunsaturated Fatty Acids Co-Extraction by a Green Process
title_full Fucoxanthin and Polyunsaturated Fatty Acids Co-Extraction by a Green Process
title_fullStr Fucoxanthin and Polyunsaturated Fatty Acids Co-Extraction by a Green Process
title_full_unstemmed Fucoxanthin and Polyunsaturated Fatty Acids Co-Extraction by a Green Process
title_short Fucoxanthin and Polyunsaturated Fatty Acids Co-Extraction by a Green Process
title_sort fucoxanthin and polyunsaturated fatty acids co-extraction by a green process
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017215/
https://www.ncbi.nlm.nih.gov/pubmed/29641444
http://dx.doi.org/10.3390/molecules23040874
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