Chemical Modification of Chitosan for Efficient Vaccine Delivery

Chitosan, which exhibits good biocompatibility, safety, microbial degradation and other excellent performances, has found application in all walks of life. In the field of medicine, usage of chitosan for the delivery of vaccine is favored by a wide range of researchers. However, due to its own natur...

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Autores principales: Xing, Lei, Fan, Ya-Tong, Zhou, Tian-Jiao, Gong, Jia-Hui, Cui, Lian-Hua, Cho, Ki-Hyun, Choi, Yun-Jaie, Jiang, Hu-Lin, Cho, Chong-Su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017229/
https://www.ncbi.nlm.nih.gov/pubmed/29370100
http://dx.doi.org/10.3390/molecules23020229
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author Xing, Lei
Fan, Ya-Tong
Zhou, Tian-Jiao
Gong, Jia-Hui
Cui, Lian-Hua
Cho, Ki-Hyun
Choi, Yun-Jaie
Jiang, Hu-Lin
Cho, Chong-Su
author_facet Xing, Lei
Fan, Ya-Tong
Zhou, Tian-Jiao
Gong, Jia-Hui
Cui, Lian-Hua
Cho, Ki-Hyun
Choi, Yun-Jaie
Jiang, Hu-Lin
Cho, Chong-Su
author_sort Xing, Lei
collection PubMed
description Chitosan, which exhibits good biocompatibility, safety, microbial degradation and other excellent performances, has found application in all walks of life. In the field of medicine, usage of chitosan for the delivery of vaccine is favored by a wide range of researchers. However, due to its own natural limitations, its application has been constrained to the beginning of study. In order to improve the applicability for vaccine delivery, researchers have carried out various chemical modifications of chitosan. This review summarizes a variety of modification methods and applications of chitosan and its derivatives in the field of vaccine delivery.
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spelling pubmed-60172292018-11-13 Chemical Modification of Chitosan for Efficient Vaccine Delivery Xing, Lei Fan, Ya-Tong Zhou, Tian-Jiao Gong, Jia-Hui Cui, Lian-Hua Cho, Ki-Hyun Choi, Yun-Jaie Jiang, Hu-Lin Cho, Chong-Su Molecules Review Chitosan, which exhibits good biocompatibility, safety, microbial degradation and other excellent performances, has found application in all walks of life. In the field of medicine, usage of chitosan for the delivery of vaccine is favored by a wide range of researchers. However, due to its own natural limitations, its application has been constrained to the beginning of study. In order to improve the applicability for vaccine delivery, researchers have carried out various chemical modifications of chitosan. This review summarizes a variety of modification methods and applications of chitosan and its derivatives in the field of vaccine delivery. MDPI 2018-01-25 /pmc/articles/PMC6017229/ /pubmed/29370100 http://dx.doi.org/10.3390/molecules23020229 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Xing, Lei
Fan, Ya-Tong
Zhou, Tian-Jiao
Gong, Jia-Hui
Cui, Lian-Hua
Cho, Ki-Hyun
Choi, Yun-Jaie
Jiang, Hu-Lin
Cho, Chong-Su
Chemical Modification of Chitosan for Efficient Vaccine Delivery
title Chemical Modification of Chitosan for Efficient Vaccine Delivery
title_full Chemical Modification of Chitosan for Efficient Vaccine Delivery
title_fullStr Chemical Modification of Chitosan for Efficient Vaccine Delivery
title_full_unstemmed Chemical Modification of Chitosan for Efficient Vaccine Delivery
title_short Chemical Modification of Chitosan for Efficient Vaccine Delivery
title_sort chemical modification of chitosan for efficient vaccine delivery
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017229/
https://www.ncbi.nlm.nih.gov/pubmed/29370100
http://dx.doi.org/10.3390/molecules23020229
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