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Novel Inhibitor Discovery of Staphylococcus aureus Sortase B and the Mechanism Confirmation via Molecular Modeling

SortaseB (SrtB) plays a critical role in Staphylococcus aureus (S. aureus) infections. According to the reports in the literature, SrtB can anchor the IsdC to the cell wall to capture iron from the host to achieve a successful invasion. On the other hand, SrtB could also affect the adhesion of S. au...

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Detalles Bibliográficos
Autores principales:	Wang, Guizhen, Wang, Xiyan, Sun, Lin, Gao, Yawen, Niu, Xiaodi, Wang, Hongsu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017250/ https://www.ncbi.nlm.nih.gov/pubmed/29690584 http://dx.doi.org/10.3390/molecules23040977

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