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Exosome-mediated transfer of lncRNA RP11-838N2.4 promotes erlotinib resistance in non-small cell lung cancer

Currently, resistance to tyrosine kinase inhibitors, such as erlotinib, has become a major obstacle for improving the clinical outcome of patients with metastatic and advanced-stage non-small cell lung cancer (NSCLC). While cell behavior can be modulated by long non-coding RNAs (lncRNAs), the roles...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Cai, Xinrui, Yu, Jie, Lu, Xuxiang, Qian, Qiuhai, Qian, Weibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017264/
https://www.ncbi.nlm.nih.gov/pubmed/29845246
http://dx.doi.org/10.3892/ijo.2018.4412