Synthesis of Two Tetrasaccharide Pentenyl Glycosides Related to the Pectic Rhamnogalacturonan I Polysaccharide

The synthesis of two protected tetrasaccharide pentenyl glycosides with diarabinan and digalactan branching related to the pectic polysaccharide rhamnogalacturonan I is reported. The strategy relies on the coupling of N-phenyl trifluoroacetimidate disaccharide donors to a common rhamnosyl acceptor....

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Detalles Bibliográficos
Autores principales: Zakharova, Alexandra N., Awan, Shahid I., Nami, Faranak, Gotfredsen, Charlotte H., Madsen, Robert, Clausen, Mads H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017268/
https://www.ncbi.nlm.nih.gov/pubmed/29401687
http://dx.doi.org/10.3390/molecules23020327
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author Zakharova, Alexandra N.
Awan, Shahid I.
Nami, Faranak
Gotfredsen, Charlotte H.
Madsen, Robert
Clausen, Mads H.
author_facet Zakharova, Alexandra N.
Awan, Shahid I.
Nami, Faranak
Gotfredsen, Charlotte H.
Madsen, Robert
Clausen, Mads H.
author_sort Zakharova, Alexandra N.
collection PubMed
description The synthesis of two protected tetrasaccharide pentenyl glycosides with diarabinan and digalactan branching related to the pectic polysaccharide rhamnogalacturonan I is reported. The strategy relies on the coupling of N-phenyl trifluoroacetimidate disaccharide donors to a common rhamnosyl acceptor. The resulting trisaccharide thioglycosides were finally coupled to an n-pentenyl galactoside acceptor to access the two protected branched tetrasaccharides.
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spelling pubmed-60172682018-11-13 Synthesis of Two Tetrasaccharide Pentenyl Glycosides Related to the Pectic Rhamnogalacturonan I Polysaccharide Zakharova, Alexandra N. Awan, Shahid I. Nami, Faranak Gotfredsen, Charlotte H. Madsen, Robert Clausen, Mads H. Molecules Article The synthesis of two protected tetrasaccharide pentenyl glycosides with diarabinan and digalactan branching related to the pectic polysaccharide rhamnogalacturonan I is reported. The strategy relies on the coupling of N-phenyl trifluoroacetimidate disaccharide donors to a common rhamnosyl acceptor. The resulting trisaccharide thioglycosides were finally coupled to an n-pentenyl galactoside acceptor to access the two protected branched tetrasaccharides. MDPI 2018-02-03 /pmc/articles/PMC6017268/ /pubmed/29401687 http://dx.doi.org/10.3390/molecules23020327 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zakharova, Alexandra N.
Awan, Shahid I.
Nami, Faranak
Gotfredsen, Charlotte H.
Madsen, Robert
Clausen, Mads H.
Synthesis of Two Tetrasaccharide Pentenyl Glycosides Related to the Pectic Rhamnogalacturonan I Polysaccharide
title Synthesis of Two Tetrasaccharide Pentenyl Glycosides Related to the Pectic Rhamnogalacturonan I Polysaccharide
title_full Synthesis of Two Tetrasaccharide Pentenyl Glycosides Related to the Pectic Rhamnogalacturonan I Polysaccharide
title_fullStr Synthesis of Two Tetrasaccharide Pentenyl Glycosides Related to the Pectic Rhamnogalacturonan I Polysaccharide
title_full_unstemmed Synthesis of Two Tetrasaccharide Pentenyl Glycosides Related to the Pectic Rhamnogalacturonan I Polysaccharide
title_short Synthesis of Two Tetrasaccharide Pentenyl Glycosides Related to the Pectic Rhamnogalacturonan I Polysaccharide
title_sort synthesis of two tetrasaccharide pentenyl glycosides related to the pectic rhamnogalacturonan i polysaccharide
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017268/
https://www.ncbi.nlm.nih.gov/pubmed/29401687
http://dx.doi.org/10.3390/molecules23020327
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