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New Drug Candidate Targeting the 4A1 Orphan Nuclear Receptor for Medullary Thyroid Cancer Therapy

Medullary thyroid cancer (MTC) is a relatively rare thyroid cancer responsible for a substantial fraction of thyroid cancer mortality. More effective therapeutic drugs with low toxicity for MTC are urgently needed. Orphan nuclear receptor 4A1 (NR4A1) plays a pivotal role in regulating the proliferat...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Liu, Wen, Wang, Qun, Li, Qinpei, Wang, Huijuan, Wang, Jun, Teng, Tieshan, Chen, Mingliang, Ji, Ailing, Li, Yanzhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017334/
https://www.ncbi.nlm.nih.gov/pubmed/29498706
http://dx.doi.org/10.3390/molecules23030565