Design, Synthesis and Biological Evaluation of New Substituted Diquinolinyl-Pyridine Ligands as Anticancer Agents by Targeting G-Quadruplex

G-quadruplexes (G4) are stacked non-canonical nucleic acid structures found in specific G-rich DNA or RNA sequences in the human genome. G4 structures are liable for various biological functions; transcription, translation, cell aging as well as diseases such as cancer. These structures are therefor...

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Detalles Bibliográficos
Autores principales: Das, Rabindra Nath, Chevret, Edith, Desplat, Vanessa, Rubio, Sandra, Mergny, Jean-Louis, Guillon, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017375/
https://www.ncbi.nlm.nih.gov/pubmed/29301210
http://dx.doi.org/10.3390/molecules23010081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017375/
https://www.ncbi.nlm.nih.gov/pubmed/29301210
http://dx.doi.org/10.3390/molecules23010081

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