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Design, Synthesis and Biological Evaluation of New Substituted Diquinolinyl-Pyridine Ligands as Anticancer Agents by Targeting G-Quadruplex

G-quadruplexes (G4) are stacked non-canonical nucleic acid structures found in specific G-rich DNA or RNA sequences in the human genome. G4 structures are liable for various biological functions; transcription, translation, cell aging as well as diseases such as cancer. These structures are therefor...

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Detalles Bibliográficos
Autores principales:	Das, Rabindra Nath, Chevret, Edith, Desplat, Vanessa, Rubio, Sandra, Mergny, Jean-Louis, Guillon, Jean
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017375/ https://www.ncbi.nlm.nih.gov/pubmed/29301210 http://dx.doi.org/10.3390/molecules23010081

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