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In Vitro ADME Properties of Two Novel Antimicrobial Peptoid-Based Compounds as Potential Agents against Canine Pyoderma

Antimicrobial peptides (AMPs) hold promise as the next generation of antimicrobial agents, but often suffer from rapid degradation in vivo. Modifying AMPs with non-proteinogenic residues such as peptoids (oligomers of N-alkylglycines) provides the potential to improve stability. We have identified t...

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Detalles Bibliográficos
Autores principales: Greco, Ines, Hummel, Bernard D., Vasir, Jaspreet, Watts, Jeffrey L., Koch, Jason, Hansen, Johannes E., Nielsen, Hanne Mørck, Damborg, Peter, Hansen, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017477/
https://www.ncbi.nlm.nih.gov/pubmed/29534469
http://dx.doi.org/10.3390/molecules23030630