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In Vitro ADME Properties of Two Novel Antimicrobial Peptoid-Based Compounds as Potential Agents against Canine Pyoderma
Antimicrobial peptides (AMPs) hold promise as the next generation of antimicrobial agents, but often suffer from rapid degradation in vivo. Modifying AMPs with non-proteinogenic residues such as peptoids (oligomers of N-alkylglycines) provides the potential to improve stability. We have identified t...
Autores principales: | Greco, Ines, Hummel, Bernard D., Vasir, Jaspreet, Watts, Jeffrey L., Koch, Jason, Hansen, Johannes E., Nielsen, Hanne Mørck, Damborg, Peter, Hansen, Paul R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017477/ https://www.ncbi.nlm.nih.gov/pubmed/29534469 http://dx.doi.org/10.3390/molecules23030630 |
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