Synthesis and Smo Activity of Some Novel Benzamide Derivatives

Two series of benzamides compounds bearing piperidine groups were synthesized and the Gli-luc luciferase activity was screened by Gys-luc luciferase gene detection method. Compound 5q showed promising inhibition of hedgehog (Hh) signaling pathway. To further verify whether the Hh inhibitory activiti...

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Detalles Bibliográficos
Autores principales: Ding, Huaiwei, Chen, Kai, Song, Bingke, Deng, Chenglong, Li, Wei, Niu, Li, Bai, Mengxuan, Song, Hongrui, Zhang, Lijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017536/
https://www.ncbi.nlm.nih.gov/pubmed/29301237
http://dx.doi.org/10.3390/molecules23010085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017536/
https://www.ncbi.nlm.nih.gov/pubmed/29301237
http://dx.doi.org/10.3390/molecules23010085

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