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Interplay between P-Glycoprotein Expression and Resistance to Endoplasmic Reticulum Stressors

Multidrug resistance (MDR) is a phenotype of cancer cells with reduced sensitivity to a wide range of unrelated drugs. P-glycoprotein (P-gp)—a drug efflux pump (ABCB1 member of the ABC transporter gene family)—is frequently observed to be a molecular cause of MDR. The drug-efflux activity of P-gp is...

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Detalles Bibliográficos
Autores principales:	Hano, Milan, Tomášová, Lenka, Šereš, Mário, Pavlíková, Lucia, Breier, Albert, Sulová, Zdena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017601/ https://www.ncbi.nlm.nih.gov/pubmed/29415493 http://dx.doi.org/10.3390/molecules23020337

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