In Silico Discovery of a Substituted 6-Methoxy-quinalidine with Leishmanicidal Activity in Leishmania infantum

There is an urgent need for the discovery of new antileishmanial drugs with a new mechanism of action. Type 2 NADH dehydrogenase from Leishmania infantum (LiNDH2) is an enzyme of the parasite’s respiratory system, which catalyzes the electron transfer from NADH to ubiquinone without coupled proton p...

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Detalles Bibliográficos
Autores principales: Stevanović, Strahinja, Perdih, Andrej, Senćanski, Milan, Glišić, Sanja, Duarte, Margarida, Tomás, Ana M., Sena, Filipa V., Sousa, Filipe M., Pereira, Manuela M., Solmajer, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017605/
https://www.ncbi.nlm.nih.gov/pubmed/29584709
http://dx.doi.org/10.3390/molecules23040772

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