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Catalytic Enantioselective Addition of Organozirconium Reagents to Aldehydes

A catalytic enantioselective addition reaction of alkylzirconium species to aromatic aldehydes is reported. The reaction, facilitated by a chiral nonracemic diol ligand complex with Ti(O(i)Pr)(4), proceeds under mild and convenient conditions, and no premade organometallic reagents are required sinc...

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Detalles Bibliográficos
Autores principales: Solà, Ricard, Veguillas, Marcos, González-Soria, María José, Carter, Nicholas, Fernández-Ibáñez, M. Angeles, Maciá, Beatriz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017622/
https://www.ncbi.nlm.nih.gov/pubmed/29677123
http://dx.doi.org/10.3390/molecules23040961