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Exploring the Chemical Diversity of Algerian Plants: Three New Pentacyclic Triterpenoids from Launaea acanthoclada Roots

The chemical study of Launaea acanthoclada from South-East Algeria led to the isolation of twelve oxygenated terpenoid compounds, including three new pentacyclic triterpenoids 1–3 with either lupane or ursane rearranged skeletons. The structure and the stereochemistry of these compounds were establi...

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Autores principales: Zergainoh, Nabila, Ciavatta, Maria Letizia, Carbone, Marianna, Bitam, Fatma, Aberkane, Mohamed Cherif, Gavagnin, Margherita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017627/
https://www.ncbi.nlm.nih.gov/pubmed/29301201
http://dx.doi.org/10.3390/molecules23010080
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author Zergainoh, Nabila
Ciavatta, Maria Letizia
Carbone, Marianna
Bitam, Fatma
Aberkane, Mohamed Cherif
Gavagnin, Margherita
author_facet Zergainoh, Nabila
Ciavatta, Maria Letizia
Carbone, Marianna
Bitam, Fatma
Aberkane, Mohamed Cherif
Gavagnin, Margherita
author_sort Zergainoh, Nabila
collection PubMed
description The chemical study of Launaea acanthoclada from South-East Algeria led to the isolation of twelve oxygenated terpenoid compounds, including three new pentacyclic triterpenoids 1–3 with either lupane or ursane rearranged skeletons. The structure and the stereochemistry of these compounds were established by spectroscopic methods, including NMR techniques. The chemical pattern of L. acanthoclada is in accordance with the triterpenoid scenario of the genus Launaea embracing to date lupane, oleane, ursane and taraxastane skeletons. However, the carbon frameworks exhibited by new compounds 1–3 have never been reported from Launaea species.
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spelling pubmed-60176272018-11-13 Exploring the Chemical Diversity of Algerian Plants: Three New Pentacyclic Triterpenoids from Launaea acanthoclada Roots Zergainoh, Nabila Ciavatta, Maria Letizia Carbone, Marianna Bitam, Fatma Aberkane, Mohamed Cherif Gavagnin, Margherita Molecules Article The chemical study of Launaea acanthoclada from South-East Algeria led to the isolation of twelve oxygenated terpenoid compounds, including three new pentacyclic triterpenoids 1–3 with either lupane or ursane rearranged skeletons. The structure and the stereochemistry of these compounds were established by spectroscopic methods, including NMR techniques. The chemical pattern of L. acanthoclada is in accordance with the triterpenoid scenario of the genus Launaea embracing to date lupane, oleane, ursane and taraxastane skeletons. However, the carbon frameworks exhibited by new compounds 1–3 have never been reported from Launaea species. MDPI 2017-12-30 /pmc/articles/PMC6017627/ /pubmed/29301201 http://dx.doi.org/10.3390/molecules23010080 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zergainoh, Nabila
Ciavatta, Maria Letizia
Carbone, Marianna
Bitam, Fatma
Aberkane, Mohamed Cherif
Gavagnin, Margherita
Exploring the Chemical Diversity of Algerian Plants: Three New Pentacyclic Triterpenoids from Launaea acanthoclada Roots
title Exploring the Chemical Diversity of Algerian Plants: Three New Pentacyclic Triterpenoids from Launaea acanthoclada Roots
title_full Exploring the Chemical Diversity of Algerian Plants: Three New Pentacyclic Triterpenoids from Launaea acanthoclada Roots
title_fullStr Exploring the Chemical Diversity of Algerian Plants: Three New Pentacyclic Triterpenoids from Launaea acanthoclada Roots
title_full_unstemmed Exploring the Chemical Diversity of Algerian Plants: Three New Pentacyclic Triterpenoids from Launaea acanthoclada Roots
title_short Exploring the Chemical Diversity of Algerian Plants: Three New Pentacyclic Triterpenoids from Launaea acanthoclada Roots
title_sort exploring the chemical diversity of algerian plants: three new pentacyclic triterpenoids from launaea acanthoclada roots
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017627/
https://www.ncbi.nlm.nih.gov/pubmed/29301201
http://dx.doi.org/10.3390/molecules23010080
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