Increasing Polarity in Tacrine and Huprine Derivatives: Potent Anticholinesterase Agents for the Treatment of Myasthenia Gravis

Symptomatic treatment of myasthenia gravis is based on the use of peripherally-acting acetylcholinesterase (AChE) inhibitors that, in some cases, must be discontinued due to the occurrence of a number of side-effects. Thus, new AChE inhibitors are being developed and investigated for their potential...

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Detalles Bibliográficos
Autores principales: Galdeano, Carles, Coquelle, Nicolas, Cieslikiewicz-Bouet, Monika, Bartolini, Manuela, Pérez, Belén, Clos, M. Victòria, Silman, Israel, Jean, Ludovic, Colletier, Jacques-Philippe, Renard, Pierre-Yves, Muñoz-Torrero, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017698/
https://www.ncbi.nlm.nih.gov/pubmed/29534488
http://dx.doi.org/10.3390/molecules23030634

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